Robot-Assisted Radical Prostatectomy for Potential Cancer Control in Patients with Metastatic Prostate Cancer
Abstract
:1. Introduction
2. Materials and Methods
2.1. Patient Population
2.2. Histopathology
2.3. Follow-Up
2.4. Endpoints and Statistical Analysis
3. Results
3.1. Patient Characteristics
3.2. Surgical and Pathological Outcomes
3.3. Oncological Outcomes
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Variables | |
---|---|
Age (year, median, IQR) | 74.5 (62.0–78.8) |
Body mass index (kg/m2, median, IQR) | 23.8 (22.5–25.0) |
Initial PSA (ng/mL, median, IQR) | 185.300 (34.944–333.379) |
Clinical T stage (number, %) | |
Biopsy Gleason score (%) | |
4 + 3 | 2 (16.7) |
4 + 4 | 2 (16.7) |
4 + 5 | 6 (49.9) |
5 + 4 | 2 (16.7) |
Clinical T stage (number, %) | |
T2 | 5 (41.7) |
T3 | 5 (41.7) |
T4 | 2 (16.6) |
Clinical N stage (number, %) | |
N0 | 5 (41.7) |
N1 | 7 (58.3) |
Clinical M stage (number, %) | |
M0 | 0 |
M1 | 12 (100) |
Metastatic sites (number, %) | |
Lymph nodes | 7 (58.3) |
Bone | 12 (100) |
Number of bone metastasis (%) | |
1 | 5 (41.7) |
3 | 5 (41.7) |
≥5 | 2 (16.6) |
Neoadjuvant therapy (number, 5) | |
Combined androgen blockade | 4 (33.3) |
ARPI | 3 (25.0) |
Chemohormonal therapy | 5 (41.7) |
Duration of neoadjuvant therapy (months, median, IQR) | 7.3 (6.1–27.2) |
Variables | |
---|---|
Proximate PSA before RARP (ng/mL, median, IQR) | 0.017 (0.007–0.194) |
Console time (min, median, IQR) | 85.0 (70.3–112.0) |
EBL (mL, median, IQR) | 23 (7–45) |
pathological T stage (number, %) | |
T0 | 5 (41.7) |
T2 | 5 (41.7) |
T3 | 2 (16.7) |
Pathological Gleason score (%) | |
0 | 5 (41.7) |
3 + 4 | 1 (8.3) |
4 + 3 | 2 (16.7) |
5 + 3 | 1 (8.3) |
Positive surgical margin (number, %) | 1 (8.3) |
Adjuvant ADT (number, %) | 3 (25.0) |
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Takagi, K.; Kawase, M.; Kato, D.; Kawase, K.; Takai, M.; Iinuma, K.; Nakane, K.; Hagiwara, N.; Yamada, T.; Tomioka, M.; et al. Robot-Assisted Radical Prostatectomy for Potential Cancer Control in Patients with Metastatic Prostate Cancer. Curr. Oncol. 2022, 29, 2864-2870. https://doi.org/10.3390/curroncol29040233
Takagi K, Kawase M, Kato D, Kawase K, Takai M, Iinuma K, Nakane K, Hagiwara N, Yamada T, Tomioka M, et al. Robot-Assisted Radical Prostatectomy for Potential Cancer Control in Patients with Metastatic Prostate Cancer. Current Oncology. 2022; 29(4):2864-2870. https://doi.org/10.3390/curroncol29040233
Chicago/Turabian StyleTakagi, Kimiaki, Makoto Kawase, Daiki Kato, Kota Kawase, Manabu Takai, Koji Iinuma, Keita Nakane, Noriyasu Hagiwara, Toru Yamada, Masayuki Tomioka, and et al. 2022. "Robot-Assisted Radical Prostatectomy for Potential Cancer Control in Patients with Metastatic Prostate Cancer" Current Oncology 29, no. 4: 2864-2870. https://doi.org/10.3390/curroncol29040233