Next Article in Journal
Spontaneous Regression of Metastatic Renal Cell Carcinoma after SARS-CoV-2 Infection: A Report of Two Cases
Previous Article in Journal
Complex Differential Diagnosis between Primary Breast Cancer and Breast Metastasis from EGFR-Mutated Lung Adenocarcinoma: Case Report and Literature Review
Review

Ampullary Carcinoma: An Overview of a Rare Entity and Discussion of Current and Future Therapeutic Challenges

1
Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni-15, 40128 Bologna, Italy
2
Medical Oncology Unit, “Mons. R. Dimiccoli” Hospital, 76121 Barletta (BT), ASL BT, Italy
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2021, 28(5), 3393-3402; https://doi.org/10.3390/curroncol28050293
Received: 5 August 2021 / Revised: 27 August 2021 / Accepted: 30 August 2021 / Published: 1 September 2021
(This article belongs to the Special Issue Hepatobiliary Malignancies: Recent Advancements and Future Directions)
Ampullary carcinomas (ACs) represent a rare entity, accounting for approximately 0.2% of all gastrointestinal solid tumors and 20% of all periampullary cancers (PACs). Unfortunately, few data are available regarding the optimal therapeutic strategy for ACs due to their rarity, and physicians frequently encounter significant difficulties in the management of these malignancies. In this review, we will provide an overview of current evidence on AC, especially focusing on biological features, histological characteristics, and available data guiding present and future therapeutic strategies for these rare, and still barely known, tumors. View Full-Text
Keywords: ampullary cancer; ampulla of Vater cancer; biliary tract cancer; chemotherapy; adenocarcinoma ampullary cancer; ampulla of Vater cancer; biliary tract cancer; chemotherapy; adenocarcinoma
Show Figures

Figure 1

MDPI and ACS Style

Rizzo, A.; Dadduzio, V.; Lombardi, L.; Ricci, A.D.; Gadaleta-Caldarola, G. Ampullary Carcinoma: An Overview of a Rare Entity and Discussion of Current and Future Therapeutic Challenges. Curr. Oncol. 2021, 28, 3393-3402. https://doi.org/10.3390/curroncol28050293

AMA Style

Rizzo A, Dadduzio V, Lombardi L, Ricci AD, Gadaleta-Caldarola G. Ampullary Carcinoma: An Overview of a Rare Entity and Discussion of Current and Future Therapeutic Challenges. Current Oncology. 2021; 28(5):3393-3402. https://doi.org/10.3390/curroncol28050293

Chicago/Turabian Style

Rizzo, Alessandro, Vincenzo Dadduzio, Lucia Lombardi, Angela D. Ricci, and Gennaro Gadaleta-Caldarola. 2021. "Ampullary Carcinoma: An Overview of a Rare Entity and Discussion of Current and Future Therapeutic Challenges" Current Oncology 28, no. 5: 3393-3402. https://doi.org/10.3390/curroncol28050293

Find Other Styles

Article Access Map by Country/Region

1
Back to TopTop