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Current Oncology
Volume 26
Issue 5
10.3747/co.26.5007
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Current Oncology is published by MDPI from Volume 28 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Multimed Inc..
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Case Report

Gemcitabine-Induced Pseudocellulitis: A Case Report and Review of the Literature

by
H. Bami
1,*,
C. Goodman
1,2,
G. Boldt
2 and
M. Vincent
1,2
1
Schulich School of Medicine and Dentistry, London Regional Cancer Program, London, ON, Canada
2
Department of Medical Oncology, London Regional Cancer Program, London, ON, Canada
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2019, 26(5), 703-706; https://doi.org/10.3747/co.26.5007
Submission received: 9 July 2019 / Revised: 7 August 2019 / Accepted: 13 September 2019 / Published: 1 October 2019

Abstract

Gemcitabine is a chemotherapeutic agent used in a wide variety of solid tumours. Known side effects include a dose-limiting myelosuppressive toxicity, mild rash, and radiation-dependent dermatitis. Rarely, localized inflammation in the form of pseudocellulitis has also been observed. We present the case of a 77-year-old woman with a history of a Whipple procedure for pancreatic adenocarcinoma who presented to the emergency department after the start of gemcitabine therapy with increased erythema, swelling, and tenderness in her lower legs. Relevant past medical history included peripheral vascular disease, dyslipidemia, and hypertension. A diagnosis of gemcitabine-induced pseudocellulitis aggravated by venous stasis was confirmed after an extensive workup. This case report and the literature review describe this rare reaction, highlighting the need for increased recognition to avoid unnecessary therapeutic intervention.
Keywords: Gemcitabine; pseudocellulitis; pancreatic adenocarcinoma Gemcitabine; pseudocellulitis; pancreatic adenocarcinoma

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MDPI and ACS Style

Bami, H.; Goodman, C.; Boldt, G.; Vincent, M. Gemcitabine-Induced Pseudocellulitis: A Case Report and Review of the Literature. Curr. Oncol. 2019, 26, 703-706. https://doi.org/10.3747/co.26.5007

AMA Style

Bami H, Goodman C, Boldt G, Vincent M. Gemcitabine-Induced Pseudocellulitis: A Case Report and Review of the Literature. Current Oncology. 2019; 26(5):703-706. https://doi.org/10.3747/co.26.5007

Chicago/Turabian Style

Bami, H., C. Goodman, G. Boldt, and M. Vincent. 2019. "Gemcitabine-Induced Pseudocellulitis: A Case Report and Review of the Literature" Current Oncology 26, no. 5: 703-706. https://doi.org/10.3747/co.26.5007

APA Style

Bami, H., Goodman, C., Boldt, G., & Vincent, M. (2019). Gemcitabine-Induced Pseudocellulitis: A Case Report and Review of the Literature. Current Oncology, 26(5), 703-706. https://doi.org/10.3747/co.26.5007

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