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Current Oncology
Volume 22
Issue 5
10.3747/co.22.2693
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Current Oncology is published by MDPI from Volume 28 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Multimed Inc..
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Case Report

Stereotactic Ablative Radiotherapy with CyberKnife for Advanced Thymic Carcinoma: A Case Report

by
C.Y. Fan
1,
W.Y. Huang
1,*,
Y.M. Jen
1,
M.J. Lin
2 and
K.T. Lin
1
1
Department of Radiation Oncology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan
2
Department of Radiation Oncology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2015, 22(5), 391-394; https://doi.org/10.3747/co.22.2693
Submission received: 3 July 2015 / Revised: 8 August 2015 / Accepted: 8 September 2015 / Published: 1 October 2015

Abstract

Thymic carcinoma is a rare but lethal mediastinal cancer. The optimal treatment for advanced thymic carcinoma is not yet established. This report is the first known of stereotactic ablative radiotherapy (sabr) with CyberKnife (Accuray, Sunnyvale, CA, U.S.A.) as definitive therapy for thymic carcinoma. The patient, a 70-year-old woman with thymic carcinoma, invasion into neighboring organs, and pleural metastases—underwent CyberKnife sabr at 40 Gy in 5 fractions for two lesions, one in the thymus and one in the right paraspinal pleura. After 61 months of observation, a partial response was observed in the irradiated fields. However, disease progression in the non-irradiated pleura was noted. The patient underwent salvage CyberKnife sabr for the four initially nonirradiated pleural lesions. Computed tomography images obtained 10 months after the salvage therapy revealed a partial response. The patient is living, with progression-free irradiated lesions and no radiation-related toxicity. CyberKnife sabr is feasible for patients who are unable to undergo either surgery or conventionally fractionated radiation therapy.
Keywords: stereotactic ablative radiotherapy; CyberKnife; thymic carcinoma stereotactic ablative radiotherapy; CyberKnife; thymic carcinoma

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MDPI and ACS Style

Fan, C.Y.; Huang, W.Y.; Jen, Y.M.; Lin, M.J.; Lin, K.T. Stereotactic Ablative Radiotherapy with CyberKnife for Advanced Thymic Carcinoma: A Case Report. Curr. Oncol. 2015, 22, 391-394. https://doi.org/10.3747/co.22.2693

AMA Style

Fan CY, Huang WY, Jen YM, Lin MJ, Lin KT. Stereotactic Ablative Radiotherapy with CyberKnife for Advanced Thymic Carcinoma: A Case Report. Current Oncology. 2015; 22(5):391-394. https://doi.org/10.3747/co.22.2693

Chicago/Turabian Style

Fan, C.Y., W.Y. Huang, Y.M. Jen, M.J. Lin, and K.T. Lin. 2015. "Stereotactic Ablative Radiotherapy with CyberKnife for Advanced Thymic Carcinoma: A Case Report" Current Oncology 22, no. 5: 391-394. https://doi.org/10.3747/co.22.2693

APA Style

Fan, C. Y., Huang, W. Y., Jen, Y. M., Lin, M. J., & Lin, K. T. (2015). Stereotactic Ablative Radiotherapy with CyberKnife for Advanced Thymic Carcinoma: A Case Report. Current Oncology, 22(5), 391-394. https://doi.org/10.3747/co.22.2693

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