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Case Report

Swallowing Function Evaluation in a Patient with Gerstmann-Sträussler-Scheinker Disease with Pro105Leu: A Case Report

Department of Dysphagia Rehabilitation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8549, Japan
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Author to whom correspondence should be addressed.
Academic Editor: Paul B. Tchounwou
Int. J. Environ. Res. Public Health 2021, 18(18), 9734; https://doi.org/10.3390/ijerph18189734
Received: 27 July 2021 / Revised: 7 September 2021 / Accepted: 13 September 2021 / Published: 15 September 2021
(This article belongs to the Collection Relationships between Oral Health Management and Systemic Health)
Gerstmann-Sträussler-Scheinker disease (GSS) is a genetic prion disease. Swallowing function evaluation in patients with GSS remains unclear. Here, we describe a case of videofluoroscopic examination of swallowing (VF) to facilitate continued oral ingestion in a patient with P105L GSS. A 67-year-old woman developed gait disturbance and Parkinsonism symptoms at the age of 54 years. Since her family wanted her to continue oral ingestion, we performed VF, which revealed impairment and preservation of the oral and pharyngeal phases, respectively. Moreover, the impairment of the oral phase was improved by adjusting the patient’s posture and food consistency. A swallowing function evaluation based on the condition of a patient with GSS may facilitate continued oral ingestion. View Full-Text
Keywords: Gerstmann-Sträussler-Scheinker disease; swallowing function; oral ingestion Gerstmann-Sträussler-Scheinker disease; swallowing function; oral ingestion
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MDPI and ACS Style

Nakane, A.; Hasegawa, S.; Ishii, M.; Tamai, T.; Moritoyo, R.; Saito, M.; Ando, M.; Tohara, H. Swallowing Function Evaluation in a Patient with Gerstmann-Sträussler-Scheinker Disease with Pro105Leu: A Case Report. Int. J. Environ. Res. Public Health 2021, 18, 9734. https://doi.org/10.3390/ijerph18189734

AMA Style

Nakane A, Hasegawa S, Ishii M, Tamai T, Moritoyo R, Saito M, Ando M, Tohara H. Swallowing Function Evaluation in a Patient with Gerstmann-Sträussler-Scheinker Disease with Pro105Leu: A Case Report. International Journal of Environmental Research and Public Health. 2021; 18(18):9734. https://doi.org/10.3390/ijerph18189734

Chicago/Turabian Style

Nakane, Ayako, Shohei Hasegawa, Miki Ishii, Tomoe Tamai, Rieko Moritoyo, Mitsuko Saito, Mariko Ando, and Haruka Tohara. 2021. "Swallowing Function Evaluation in a Patient with Gerstmann-Sträussler-Scheinker Disease with Pro105Leu: A Case Report" International Journal of Environmental Research and Public Health 18, no. 18: 9734. https://doi.org/10.3390/ijerph18189734

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