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Physicians’ Knowledge, Attitude and Practice of Generic Substitution in China: A Cross-Sectional Online Survey

The Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmacy, Xi’an Jiaotong University, Xi’an 710000, China
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Academic Editors: Sotiris Soulis, Aspasia Goula, Evridiki Kaba and Martha Kelesi
Int. J. Environ. Res. Public Health 2021, 18(15), 7749; https://doi.org/10.3390/ijerph18157749
Received: 8 May 2021 / Revised: 16 June 2021 / Accepted: 17 June 2021 / Published: 21 July 2021
(This article belongs to the Special Issue Innovations in Health Economics, Social Policy and Health Management)
The purpose of this study is to investigate physicians’ knowledge, attitudes and practice of generic medicine substitutions in China. We conducted a cross-sectional online questionnaire survey on physicians from secondary or tertiary hospitals in China from 2020 December to 2021 April. Descriptive statistical and ordered logistic regression were used for analysis. A total of 1225 physicians were included in the final analysis, and only 330 (26.94%) of them scored 4 or above in the knowledge part, which means that the physicians have a good knowledge of generic substitutions. Of the total, 586 (47.83%) agreed or strongly agreed that generic drugs could be substituted for originator drugs and 585 (47.75%) always or often prescribed generic medicines. The percentage of physicians with a positive attitude toward or that practice prescribing generic medicine is below 50%, which needs to be improved in China. Physicians’ knowledge, their attitude toward generic substitution, if familiar with the policy of generic substitution, and incentives for prescribing generic medicines are influencing factors for the practice of generic substitution. Our studies show that the practice of generic substitution by physicians could be improved by several measures in China. We suggested that the physicians should be taught more about the bulk-buy policy and the generic-originator equivalence evaluation policy. Moreover, government incentives to promote generic substitution should be established. Our study also suggested that physicians with less working experience and female physicians should learn more about generic substitution. View Full-Text
Keywords: knowledge; attitudes and practice; generic substitution; originator; prescribe; physician knowledge; attitudes and practice; generic substitution; originator; prescribe; physician
MDPI and ACS Style

Zhao, M.; Zhang, L.; Feng, Z.; Fang, Y. Physicians’ Knowledge, Attitude and Practice of Generic Substitution in China: A Cross-Sectional Online Survey. Int. J. Environ. Res. Public Health 2021, 18, 7749. https://doi.org/10.3390/ijerph18157749

AMA Style

Zhao M, Zhang L, Feng Z, Fang Y. Physicians’ Knowledge, Attitude and Practice of Generic Substitution in China: A Cross-Sectional Online Survey. International Journal of Environmental Research and Public Health. 2021; 18(15):7749. https://doi.org/10.3390/ijerph18157749

Chicago/Turabian Style

Zhao, Mingyue, Lingyi Zhang, Zhitong Feng, and Yu Fang. 2021. "Physicians’ Knowledge, Attitude and Practice of Generic Substitution in China: A Cross-Sectional Online Survey" International Journal of Environmental Research and Public Health 18, no. 15: 7749. https://doi.org/10.3390/ijerph18157749

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