Determination of Propane-1,3-sultone in Workplace Air for Occupational Exposure Assessment
2. Materials and Methods
2.2. Material and Reagents
3.2. Conditions for Chromatographic Determination
3.3. Examination of Extraction Rate
3.4. Calibration and Precision
3.5. Validation of the Method
- b—slope coefficient of the calibration curve, so—standard deviation.
- The LOQ value calculated as a multiple of the LOD value, from the following formula:
- Vp—is the precision of the sampling device (Vp = ± 5%);
- Vz—mean precision of three levels of ranges, which has been calculated using the formula:
4. Results and Discussion
4.1. Testing of Air Sampling Conditions
4.2. Determination of Extraction Rate
4.3. Calibration and Precision
4.4. Sample Storage
Conflicts of Interest
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|Air Flow Rate [L/min]||Sampling Time [min]||Approximate Substance Concentration in the Air [mg/m3]||Area of PS Peaks in Solutions after Desorption||Quantity of the Substance in Layer II of XAD-2 (in % of the Quantity Determined in Layer I)|
|Glass Fiber||Layer I||Layer II|
|2||360||pure substance||no peaks||4,346,325||490,610||11|
|1||360||pure substance||no peaks||11,124,567||1,333,226||12|
|Air Flow Rate [L/min]||Sampling Time [min]||Approximate Substance Concentration in the Air [mg/m3]||Area of PS Peaks in Solutions after Extraction with Acetonitrile (1 mL)|
|Glass Fiber||Glass Fiber Filter||Gel Layer I||Gel Layer II|
|1||60||pure substance||no peaks||47,141||210,340||no peaks|
|1||360||0.08||no peaks||3629||530,567||no peaks|
|1||360||0.04||no peaks||3356||231,738||no peaks|
|Mass of PS Applied to the Adsorption Tube [µg]||Average Peak Area of Extracted Solutions||Average Peak Area of the Comparative Solutions||Average Extraction Coefficient|
|Tube No.||Storage Place||Storage Time [Number of Days]||Average Peak Area of the PS||Two-Tube Average||Standard Deviation|
|Measurement range||0.7 ÷ 14 µg/m3|
|Sampled air volume||360 L|
|Range of calibration curve||0.252 ÷ 5.04 µg/mL|
|Limit of detection (LOD)||4.82 ng/mL (13 ng/m3)|
|Limit of quantitation (LOQ)||14.46 ng/mL (40 ng/m3)|
|Overall precision of examination||5.99%|
|Relative total uncertainty||13%|
|Relative expanded uncertainty||26%|
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Jeżewska, A. Determination of Propane-1,3-sultone in Workplace Air for Occupational Exposure Assessment. Int. J. Environ. Res. Public Health 2020, 17, 1414. https://doi.org/10.3390/ijerph17041414
Jeżewska A. Determination of Propane-1,3-sultone in Workplace Air for Occupational Exposure Assessment. International Journal of Environmental Research and Public Health. 2020; 17(4):1414. https://doi.org/10.3390/ijerph17041414Chicago/Turabian Style
Jeżewska, Anna. 2020. "Determination of Propane-1,3-sultone in Workplace Air for Occupational Exposure Assessment" International Journal of Environmental Research and Public Health 17, no. 4: 1414. https://doi.org/10.3390/ijerph17041414