Next Article in Journal
Understanding the Barriers and Pathways to Male Help-Seeking and Help-Offering: A Mixed Methods Study of the Impact of the Mates in Construction Program
Next Article in Special Issue
Frailty and Sarcopenia as a Geriatric Syndrome in Community-Dwelling Older Adults
Previous Article in Journal
College Students’ Experience of a Food Safety Class and Their Responses to the MSG Issue
Previous Article in Special Issue
Instrumental Activities of Daily Living: The Processes Involved in and Performance of These Activities by Japanese Community-Dwelling Older Adults with Subjective Memory Complaints
Open AccessArticle

Association Between Carotid Artery Intima-Media Thickness and Combinations of Mild Cognitive Impairment and Pre-Frailty in Older Adults

by Jinkee Park 1,†, Jong-Hwan Park 2,† and Hyuntae Park 3,4,*
1
Department of Sport Rehabilitation, Dong-Ju College, Busan 49318, Korea
2
Health Convergence Medicine Research Group, Biomedical Research Institute, Pusan National University Hospital, 179, Gudeok-Ro, Seo-Gu, Busan 49241, Korea
3
Department of Health Care Science, Dong-A University, Busan 49315, Korea
4
Institute of Convergence Bio-Health, Dong-A University, Busan 49201, Korea
*
Author to whom correspondence should be addressed.
Both authors contributed equally to this manuscript.
Int. J. Environ. Res. Public Health 2019, 16(16), 2978; https://doi.org/10.3390/ijerph16162978
Received: 30 June 2019 / Revised: 10 August 2019 / Accepted: 11 August 2019 / Published: 19 August 2019
(This article belongs to the Special Issue Geriatrics Syndromes Prevention)
Carotid intima-media thickness (CIMT) has been proposed as a surrogate marker of cardiovascular disease. Mild cognitive impairment (MCI) and pre-frailty are reportedly associated with increased CIMT. As the evidence on the association of CIMT with combinations of MCI and pre-frailty is limited, this association is examined. A total of 231 older adults participated. MCI was defined according to clinical consensus or psychometric criteria by a dementia specialist, and considering detailed neuropsychological assessments. Also, pre-frailty was defined as subjects with frail component of 1 or 2. Carotid variables were measured using a B-mode ultrasound. The analysis of covariance (ANCOVA) was performed to assess independent differences in CIMT among the four groups, according to the cognitive function and frailty status after a multivariate adjustment. Increased CIMT is associated with combinations of MCI and pre-frailty. ANCOVA showed that CIMTs were significantly different among the four groups according to the cognitive function and frailty status. CIMTmax combined with MCI and pre-frailty was the thickest (1.04 ± 0.3 mm), whereas the CIMT of no MCI and no pre-frailty was the thinnest (0.82 ± 0.2 mm). The results suggest that combinations of MCI and pre-frailty are associated with increased CIMT in older adults. View Full-Text
Keywords: mild cognitive impairment; pre-frailty; carotid intima-media thickness; cardiovascular disease; older adults mild cognitive impairment; pre-frailty; carotid intima-media thickness; cardiovascular disease; older adults
Show Figures

Figure 1

MDPI and ACS Style

Park, J.; Park, J.-H.; Park, H. Association Between Carotid Artery Intima-Media Thickness and Combinations of Mild Cognitive Impairment and Pre-Frailty in Older Adults. Int. J. Environ. Res. Public Health 2019, 16, 2978.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop