New Benthic Cyanobacteria from Guadeloupe Mangroves as Producers of Antimicrobials
Molécules de Communication et Adaptation des Microorganismes, UMR 7245 CNRS, Muséum National d’Histoire Naturelle, 57 rue Cuvier (CP54), 75005 Paris, France
Institut Universitaire de France, 75005 Paris, France
Équipe “Pharmacognosie-Chimie des Substances Naturelles” BioCIS, CNRS, Université Paris-Saclay 5 rue Jean-Baptiste Clément, 92290 Châtenay-Malabry, France
UMR 7205 ISYEB et Université des Antilles, Pointe à Pitre, 97157 Guadeloupe, France
Authors to whom correspondence should be addressed.
Mar. Drugs 2020, 18(1), 16; https://doi.org/10.3390/md18010016
Received: 27 November 2019 / Revised: 17 December 2019 / Accepted: 19 December 2019 / Published: 23 December 2019
(This article belongs to the Special Issue Selected Papers from XVI MaNaPro and XI ECMNP)
Benthic cyanobacteria strains from Guadeloupe have been investigated for the first time by combining phylogenetic, chemical and biological studies in order to better understand the taxonomic and chemical diversity as well as the biological activities of these cyanobacteria through the effect of their specialized metabolites. Therefore, in addition to the construction of the phylogenetic tree, indicating the presence of 12 potentially new species, an LC-MS/MS data analysis workflow was applied to provide an overview on chemical diversity of 20 cyanobacterial extracts, which was linked to antimicrobial activities evaluation against human pathogenic and ichtyopathogenic environmental strains.