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Enzymes from Marine Polar Regions and Their Biotechnological Applications

Department of Food and Drug, University of Parma, Parco Area delle Scienze 23A, 43124 Parma, Italy
Institute of Biosciences and BioResources (IBBR), CNR, Via Pietro Castellino 111, 80131 Napoli, Italy
Department of Marine Biotechnology, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Napoli, Italy
Author to whom correspondence should be addressed.
Mar. Drugs 2019, 17(10), 544;
Received: 2 August 2019 / Revised: 17 September 2019 / Accepted: 18 September 2019 / Published: 23 September 2019
(This article belongs to the Special Issue Bioactive Molecules from Extreme Environments)
The microorganisms that evolved at low temperatures express cold-adapted enzymes endowed with unique catalytic properties in comparison to their mesophilic homologues, i.e., higher catalytic efficiency, improved flexibility, and lower thermal stability. Cold environments are therefore an attractive research area for the discovery of enzymes to be used for investigational and industrial applications in which such properties are desirable. In this work, we will review the literature on cold-adapted enzymes specifically focusing on those discovered in the bioprospecting of polar marine environments, so far largely neglected because of their limited accessibility. We will discuss their existing or proposed biotechnological applications within the framework of the more general applications of cold-adapted enzymes. View Full-Text
Keywords: Arctic/Antarctic environment; biocatalysis; cold-adaptation; marine biotechnology Arctic/Antarctic environment; biocatalysis; cold-adaptation; marine biotechnology
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Bruno, S.; Coppola, D.; di Prisco, G.; Giordano, D.; Verde, C. Enzymes from Marine Polar Regions and Their Biotechnological Applications. Mar. Drugs 2019, 17, 544.

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