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Mar. Drugs 2018, 16(6), 211; https://doi.org/10.3390/md16060211

Collagen from Cartilaginous Fish By-Products for a Potential Application in Bioactive Film Composite

1
Laboratory of Blue Biotechnology & Aquatic Bioproducts, Institut National des Sciences et Technologies de la Mer (INSTM), INSTM, 28, rue 2 mars 1934, Salammbô, Tunis 2025, Tunisia
2
Institut National Agronomique de Tunisie (INAT), Université de Carthage, Tunis 1082, Tunisia
*
Author to whom correspondence should be addressed.
Received: 2 May 2018 / Revised: 17 May 2018 / Accepted: 21 May 2018 / Published: 15 June 2018
(This article belongs to the Special Issue Collagen from Marine Biological Source and Medical Applications)
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Abstract

The acid solubilised collagen (ASC) and pepsin solubilised collagen (PSC) were extracted from the by-products (skin) of a cartilaginous fish (Mustelus mustelus). The ASC and PSC yields were 23.07% and 35.27% dry weight, respectively and were identified as collagen Type I with the presence of α, β and γ chains. As revealed by the Fourier Transform Infrared (FTIR) spectra analysis, pepsin did not alter the PSC triple helix structure. Based on the various type of collagen yield, only PSC was used in combination with chitosan to produce a composite film. Such film had lower tensile strength but higher elongation at break when compared to chitosan film; and lower water solubility and lightness when compared to collagen film. Equally, FTIR spectra analysis of film composite showed the occurrence of collagen-chitosan interaction resulting in a modification of the secondary structure of collagen. Collagen-chitosan-based biofilm showed a potential UV barrier properties and antioxidant activity, which might be used as green bioactive films to preserve nutraceutical products. View Full-Text
Keywords: cartilaginous fish by-products; collagen; chitosan; composite films; properties cartilaginous fish by-products; collagen; chitosan; composite films; properties
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Ben Slimane, E.; Sadok, S. Collagen from Cartilaginous Fish By-Products for a Potential Application in Bioactive Film Composite. Mar. Drugs 2018, 16, 211.

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