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Seaweed Bioactive Compounds against Pathogens and Microalgae: Potential Uses on Pharmacology and Harmful Algae Bloom Control

Laboratory of Biology and Biotechnology of Microorganisms, Faculty of Sciences Semlalia Marrakech, Cadi Ayyad University, Av. Prince My Abdellah P.O. Box 2390, Marrakech 40000, Morocco
Polydisciplinary Faculty of Khouribga (FPK), University Hassan 1, BP. 145, Khouribga 25000, Morocco
Departament of Biology, Faculty of Sciences, University of Porto, Rua do Campo Alegre, 4169-007 Porto, Portugal
CIIMAR, Interdisciplinary Centre of Marine and Environmental Research, Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos, s/n, 4450-208 Matosinhos, Portugal
Author to whom correspondence should be addressed.
Mar. Drugs 2018, 16(2), 55;
Received: 29 November 2017 / Revised: 2 February 2018 / Accepted: 6 February 2018 / Published: 9 February 2018
(This article belongs to the Special Issue Seaweeds and Their Biological Actions)
PDF [1229 KB, uploaded 9 February 2018]


Cyanobacteria are found globally due to their adaptation to various environments. The occurrence of cyanobacterial blooms is not a new phenomenon. The bloom-forming and toxin-producing species have been a persistent nuisance all over the world over the last decades. Evidence suggests that this trend might be attributed to a complex interplay of direct and indirect anthropogenic influences. To control cyanobacterial blooms, various strategies, including physical, chemical, and biological methods have been proposed. Nevertheless, the use of those strategies is usually not effective. The isolation of natural compounds from many aquatic and terrestrial plants and seaweeds has become an alternative approach for controlling harmful algae in aquatic systems. Seaweeds have received attention from scientists because of their bioactive compounds with antibacterial, antifungal, anti-microalgae, and antioxidant properties. The undesirable effects of cyanobacteria proliferations and potential control methods are here reviewed, focusing on the use of potent bioactive compounds, isolated from seaweeds, against microalgae and cyanobacteria growth. View Full-Text
Keywords: cyanobacteria; harmful algae bloom; control; microalgae; macroalgae; bioactive compounds cyanobacteria; harmful algae bloom; control; microalgae; macroalgae; bioactive compounds

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Zerrifi, S.E.A.; El Khalloufi, F.; Oudra, B.; Vasconcelos, V. Seaweed Bioactive Compounds against Pathogens and Microalgae: Potential Uses on Pharmacology and Harmful Algae Bloom Control. Mar. Drugs 2018, 16, 55.

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