Diphenyl Ethers from a Marine-Derived Aspergillus sydowii
AbstractSix new diphenyl ethers (1–6) along with eleven known analogs were isolated from the ethyl acetate extract of a marine-derived Aspergillus sydowii guided by LC-UV-MS. Their structures were unambiguously characterized by HRESIMS, NMR, as well as chemical derivatization. Compounds 1 and 2 are rare diphenyl ether glycosides containing d-ribose. The absolute configuration of the sugar moieties in compounds 1–3 was determined by a LC-MS method. All the compounds were evaluated for their cytotoxicities against eight cancer cell lines, including 4T1, U937, PC3, HL-60, HT-29, A549, NCI-H460, and K562, and compounds 1, 5, 6, and 8–11 were found to exhibit selective cytotoxicity against different cancer cell lines. View Full-Text
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Wang, Y.-N.; Mou, Y.-H.; Dong, Y.; Wu, Y.; Liu, B.-Y.; Bai, J.; Yan, D.-J.; Zhang, L.; Feng, D.-Q.; Pei, Y.-H.; Hu, Y.-C. Diphenyl Ethers from a Marine-Derived Aspergillus sydowii. Mar. Drugs 2018, 16, 451.
Wang Y-N, Mou Y-H, Dong Y, Wu Y, Liu B-Y, Bai J, Yan D-J, Zhang L, Feng D-Q, Pei Y-H, Hu Y-C. Diphenyl Ethers from a Marine-Derived Aspergillus sydowii. Marine Drugs. 2018; 16(11):451.Chicago/Turabian Style
Wang, Ya-Nan; Mou, Yan-Hua; Dong, Yu; Wu, Yan; Liu, Bing-Yu; Bai, Jian; Yan, Dao-Jiang; Zhang, Le; Feng, Dan-Qing; Pei, Yue-Hu; Hu, You-Cai. 2018. "Diphenyl Ethers from a Marine-Derived Aspergillus sydowii." Mar. Drugs 16, no. 11: 451.
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