Next Article in Journal
Upregulation and Identification of Antibiotic Activity of a Marine-Derived Streptomyces sp. via Co-Cultures with Human Pathogens
Next Article in Special Issue
New 2-Methoxy Acetylenic Acids and Pyrazole Alkaloids from the Marine Sponge Cinachyrella sp.
Previous Article in Journal
Marine Inspired 2-(5-Halo-1H-indol-3-yl)-N,N-dimethylethanamines as Modulators of Serotonin Receptors: An Example Illustrating the Power of Bromine as Part of the Uniquely Marine Chemical Space
Previous Article in Special Issue
Antibacterial Activity of AI-Hemocidin 2, a Novel N-Terminal Peptide of Hemoglobin Purified from Arca inflata

Two Furanosesterterpenoids from the Sponge Luffariella variabilis

Department of Chemistry, Biology and Marine Science, University of the Ryukyus, Nishihara, Okinawa 903-0213, Japan
Naturalis Biodiversity Center, P.O. Box 9517, 2300 RA Leiden, The Netherlands
Author to whom correspondence should be addressed.
Mar. Drugs 2017, 15(8), 249;
Received: 3 July 2017 / Revised: 3 August 2017 / Accepted: 7 August 2017 / Published: 10 August 2017
(This article belongs to the Collection Bioactive Compounds from Marine Invertebrates)
Two new sesterterpenoids, 1 and 2, were isolated from the sponge Luffariella variabilis. Their planar structures were characterized with spectroscopic analyses. The sole chiral center of compound 1 was elucidated as 12R by comparing observed and calculated optical rotation values. The configurations of compound 2 were determined by NMR and electronic circular dichroism (ECD) studies. Furthermore, compound 2 showed cytotoxicity at IC50 1.0 µM against NBT-T2 cells. View Full-Text
Keywords: sesterterpenoid; sponge; cytotoxicity sesterterpenoid; sponge; cytotoxicity
Show Figures

Graphical abstract

MDPI and ACS Style

Ahmadi, P.; Higashi, M.; Voogd, N.J.d.; Tanaka, J. Two Furanosesterterpenoids from the Sponge Luffariella variabilis. Mar. Drugs 2017, 15, 249.

AMA Style

Ahmadi P, Higashi M, Voogd NJd, Tanaka J. Two Furanosesterterpenoids from the Sponge Luffariella variabilis. Marine Drugs. 2017; 15(8):249.

Chicago/Turabian Style

Ahmadi, Peni, Masahiro Higashi, Nicole J. de Voogd, and Junichi Tanaka. 2017. "Two Furanosesterterpenoids from the Sponge Luffariella variabilis" Marine Drugs 15, no. 8: 249.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop