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Mar. Drugs 2016, 14(8), 145;

Fucoidans in Nanomedicine

Inserm, U1148, LVTS, University Paris Diderot, X Bichat Hospital, F-75877 Paris, France
Galilée Institute, University Paris 13, Sorbonne Paris Cité, F-93430 Villetaneuse, France
Algues & Mer, Kernigou, F-29242 Ouessant, France
These authors contributed equally to this work.
Author to whom correspondence should be addressed.
Academic Editor: Paola Laurienzo
Received: 17 June 2016 / Revised: 20 July 2016 / Accepted: 21 July 2016 / Published: 29 July 2016
(This article belongs to the Collection Marine Polysaccharides)
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Fucoidans are widespread cost-effective sulfated marine polysaccharides which have raised interest in the scientific community over last decades for their wide spectrum of bioactivities. Unsurprisingly, nanomedicine has grasped these compounds to develop innovative therapeutic and diagnostic nanosystems. The applications of fucoidans in nanomedicine as imaging agents, drug carriers or for their intrinsic properties are reviewed here after a short presentation of the main structural data and biological properties of fucoidans. The origin and the physicochemical specifications of fucoidans are summarized in order to discuss the strategy of fucoidan-containing nanosystems in Human health. Currently, there is a need for reproducible, well characterized fucoidan fractions to ensure significant progress. View Full-Text
Keywords: fucoidans; nanomedicine; sulfated polysaccharides; nanosystems; drug delivery; imaging agent; tissue regeneration fucoidans; nanomedicine; sulfated polysaccharides; nanosystems; drug delivery; imaging agent; tissue regeneration

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Chollet, L.; Saboural, P.; Chauvierre, C.; Villemin, J.-N.; Letourneur, D.; Chaubet, F. Fucoidans in Nanomedicine. Mar. Drugs 2016, 14, 145.

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