Why Our Youth Vape?—A Trend Analysis Based on Cross-Sectional Annual Surveys of Middle and High School Students in the U.S.
Abstract
1. Introduction
- (1)
- Analyzing vaping prevalence, including overall trends, gender-specific patterns, comparisons between middle and high school students, and differences across individual grade levels.
- (2)
- Investigating exclusive e-cigarette use, exclusive traditional cigarette smoking, and the overlap between the two behaviors.
- (3)
- Identifying key reasons gender-wise for adolescents for first using or continuing to use e-cigarettes.
- (4)
- A pupil is provided with a list of reasons for vaping to begin with and also when he/she becomes a habitual user. Examine how the choice is impacted by gender. This is a complex problem because a pupil can check more than one reason for starting to vaping.
- A.
- Have you ever used e-cigarettes, even once or twice?
- B.
- What was the reason you used e-cigarettes for the first time?
- C.
- What is the reason for your current use of e-cigarettes?
2. Materials and Methods
- I exclusively;
- II exclusively;
- III exclusively;
- IV exclusively;
- I and II exclusively;
- I and III exclusively;
- I and IV exclusively;
- II and III exclusively;
- II and IV exclusively;
- III and IV exclusively;
- I, II, and III exclusively;
- I, II, and IV exclusively;
- I, III, and IV exclusively;
- I, II, and IV exclusively;
- I, II, III, and IV.
3. Results
3.1. Trend Analysis
3.1.1. Overall Trend
3.1.2. Trend by Gender
3.1.3. Trend by School Type
3.1.4. Trend by Grade
3.2. Comparison of Trend in Exclusive Cigarette and E-Cigarette Use
- Group α: Neither cigarette nor e-cigarette users;
- Group β: Cigarette users only;
- Group γ: E-cigarette users only;
- Group δ: Users of both cigarettes and e-cigarettes.
3.3. Reasons for Vaping
- Question B: “What was the reason you used e-cigarettes for the first time?”
- Question C: “What is the reason for your current use of e-cigarettes?”
- i.
- The overall number of student e-cigarette users peaked in 2019, followed by a consistent decline.
- ii.
- From 2018 to 2021, male students exhibited higher rates of vaping than females; however, this trend reversed in 2022 and 2023.
- iii.
- High school students reported higher rates of e-cigarette use compared to their middle school counterparts.
- iv.
- Among all grade levels, 12th-grade students consistently had the highest rates of use.
- v.
- vi.
- Importantly, mental stress, particularly anxiety—emerged as one of the top three self-reported reasons for initiating e-cigarette use, indicating that stress management, rather than smoking cessation, may be a primary motivator.
4. Discussion
5. Conclusions
6. Limitations
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
| ENDS | Electronic nicotine delivery systems |
| NYTS | National Youth Tobacco Survey |
| CDC | Centers for Disease Control and Prevention |
| FDA | Food and Drug Administration |
References
- Sharma, S.; Meister, M.; Weaver, S.; Zelikoff, J.; Bell-Huff, C.; Black, M.; Shannahan, J.; Wright, C. The beginning of ENDS (electronic nicotine delivery systems): Origins, trends, and regulatory considerations. Inhal. Toxicol. 2025, 37, 417–425. [Google Scholar] [CrossRef]
- Ibukun, O.; Kumbalatara, C.; Jayawardene, W. Adolescent Perceptions and Use of E-Cigarettes as Smoking Cessation Tools and for Pleasure: Data Analysis from National Youth Tobacco Survey (NYTS), 2011, 2015, 2019, and 2023. Societies 2025, 15, 201. [Google Scholar] [CrossRef]
- Cooper, M. Notes from the field: E-cigarette use among middle and high school students—United States, 2022. MMWR Morb. Mortal. Wkly. Rep. 2022, 71, 1283–1285. [Google Scholar] [CrossRef] [PubMed]
- Hill, J.E.; Rao, M.B.; Guan, T. Vaping: The Key to Quitting Cigarettes or a Gateway to Addiction? Medicina 2024, 60, 1541. [Google Scholar] [CrossRef] [PubMed]
- Cullen, K.A.; Gentzke, A.S.; Sawdey, M.D.; Chang, J.T.; Anic, G.M.; Wang, T.W.; Creamer, M.R.; Jamal, A.; Ambrose, B.K.; King, B.A. E-cigarette use among youth in the United States, 2019. JAMA 2019, 322, 2095–2103. [Google Scholar] [CrossRef] [PubMed]
- Cullen, K.A. Notes from the field: Use of electronic cigarettes and any tobacco product among middle and high school students—United States, 2011–2018. MMWR Morb. Mortal. Wkly. Rep. 2018, 67, 1276–1277. [Google Scholar] [CrossRef]
- Centers for Disease Control and Prevention. National Youth Tobacco Survey (NYTS) Methodology Report; Office on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion: Washington, DC, USA, 2023.
- Park-Lee, E. Notes from the field: E-cigarette use among middle and high school students—National Youth Tobacco Survey, United States, 2021. MMWR Morb. Mortal. Wkly. Rep. 2021, 70, 1387–1389. [Google Scholar] [CrossRef]
- Yan, D.; Wang, Z.; Laestadius, L.; Mosalpuria, K.; A Wilson, F.; Yan, A.; Lv, X.; Zhang, X.; Bhuyan, S.S.; Wang, Y. A systematic review for the impacts of global approaches to regulating electronic nicotine products. J. Glob. Health 2023, 13, 04076. [Google Scholar] [CrossRef]
- Sapru, S.; Vardhan, M.; Li, Q.; Guo, Y.; Li, X.; Saxena, D. E-cigarettes use in the United States: Reasons for use, perceptions, and effects on health. BMC Public Health 2020, 20, 1518. [Google Scholar] [CrossRef]
- Ali, F.R.M.; Diaz, M.C.; Armour, B.S.; Crane, E.; Tynan, M.A.; Marynak, K.L. Trends in US E-cigarette Sales Measured in Milligrams of Nicotine, 2019–2024. Am. J. Prev. Med. 2025, 68, 1173–1178. [Google Scholar] [CrossRef]
- Centers for Disease Control and Prevention. About E-Cigarettes (Vapes). Smoking and Tobacco Use. 2025. Available online: https://www.cdc.gov/tobacco/e-cigarettes/about.html (accessed on 5 November 2025).
- National Institute of Justice. The Evolution and Impact of Electronic Cigarettes. 2025. Available online: https://nij.ojp.gov/topics/articles/evolution-and-impact-electronic-cigarettes (accessed on 5 November 2025).
- Historical Timeline of Electronic Cigarettes. CASAA. Available online: https://casaa.org/education/vaping/historical-timeline-of-electronic-cigarettes/ (accessed on 5 November 2025).
- Nayak, P.; Kemp, C.B.; Redmon, P. A qualitative study of vape shop operators’ perceptions of risks and benefits of e-cigarette use and attitude toward their potential regulation by the US Food and Drug Administration, Florida, Georgia, South Carolina, or North Carolina, 2015. Prev. Chronic Dis. 2016, 13, E68. [Google Scholar] [CrossRef]
- Centers for Disease Control and Prevention. Why Youth Vape. Smoking and Tobacco Use. 2024. Available online: https://www.cdc.gov/tobacco/e-cigarettes/why-youth-vape.html (accessed on 5 November 2025).
- Office on Smoking and Health; National Center for Chronic Disease Prevention and Health Promotion (US). E-Cigarette Use Among Youth and Young Adults: A Report of the Surgeon General; Office on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion: Washington, DC, USA, 2016.
- Aly, A.S.; Mamikutty, R.; Marhazlinda, J. Association between harmful and addictive perceptions of e-cigarettes and e-cigarette use among adolescents and youth—A systematic review and meta-analysis. Children 2022, 9, 1678. [Google Scholar] [CrossRef] [PubMed]
- Tao, X.; Zhang, J.; Meng, Q.; Chu, J.; Zhao, R.; Liu, Y.; Dong, Y.; Xu, H.; Tian, T.; Cui, J.; et al. The potential health effects associated with electronic-cigarette. Environ. Res. 2024, 245, 118056. [Google Scholar] [CrossRef]
- American Lung Association. Health Risks of E-Cigarettes and Vaping. 2025. Available online: https://www.lung.org/quit-smoking/e-cigarettes-vaping/impact-of-e-cigarettes-on-lung (accessed on 5 November 2025).
- Agresti, A.; Kateri, M. Categorical data analysis. In International Encyclopedia of Statistical Science; Springer: Berlin/Heidelberg, Germany, 2011; pp. 206–208. [Google Scholar]
- Anscombe, F.J. The transformation of Poisson, binomial and negative-binomial data. Biometrika 1948, 35, 246–254. [Google Scholar] [CrossRef]
- Bartlett, M.S. The use of transformations. Biometrics 1947, 3, 39–52. [Google Scholar] [CrossRef]
- Glantz, S.; Lempert, L.K. Vuse Solo e-cigarettes do not provide net benefits to public health: A scientific analysis of FDA’s marketing authorisation. Tob. Control 2024, 33, e108–e115. [Google Scholar] [CrossRef] [PubMed]
- Burrows, D.S. Younger Adult Smokers: Strategies and Opportunities; RJ Reynolds Tobacco Company Internal Document; RJ Reynolds Tobacco Company: Winston-Salem, NC, USA, 1984. [Google Scholar]
- American Lung Association. 10 Really Bad Things the Tobacco Industry Has Done–and Is Doing to Entice Kids to Start Smoking. 2024. Available online: https://www.lung.org/research/sotc/by-the-numbers/10-bad-things-to-entice-kids (accessed on 17 September 2025).
- Collins, L.; Glasser, A.M.; Abudayyeh, H.; Pearson, J.L.; Villanti, A.C. E-cigarette marketing and communication: How e-cigarette companies market e-cigarettes and the public engages with e-cigarette information. Nicotine Tob. Res. 2019, 21, 14–24. [Google Scholar] [CrossRef] [PubMed]
- Han, E.; Lempert, L.K.; Vescia, F.; Halpern-Felsher, B. Concerns over vuse e-cigarette digital marketing and implications for public health regulation: Content analysis. JMIR Form. Res. 2024, 8, e54661. [Google Scholar] [CrossRef]
- Fadus, M.C.; Smith, T.T.; Squeglia, L.M. The rise of e-cigarettes, pod mod devices, and JUUL among youth: Factors influencing use, health implications, and downstream effects. Drug Alcohol Depend. 2019, 201, 85–93. [Google Scholar] [CrossRef]
- Truth Initiative. E-cigarettes: Facts, Stats and Regulations. 2025. Available online: https://truthinitiative.org/research-resources/emerging-tobacco-products/e-cigarettes-facts-stats-and-regulations (accessed on 5 November 2025).
- Vaping360. Vape Bans: E-Cigarette Restrictions in the U.S. and Worldwide. 2025. Available online: https://vaping360.com/learn/countries-where-vaping-is-banned-illegal/ (accessed on 5 November 2025).
- CSP Daily News. California Seeks to Ban Disposable E-Cigarettes. 2025. Available online: https://cspdailynews.com/tobacco/california-seeks-ban-disposable-e-cigarettes (accessed on 5 November 2025).
- Ecigator. Jersey Bans Disposable Vapes Starting in 2025. 2024. Available online: https://ecigator.com/news/jersey-bans-disposable-vapes/ (accessed on 5 November 2025).
- European Commission. Smoke-Free Environments—Public Health. 2024. Available online: https://health.ec.europa.eu/tobacco/smoke-free-environments_en (accessed on 5 November 2025).
- Shahab, L.; Goniewicz, M.L.; Blount, B.C.; Brown, J.; McNeill, A.; Alwis, K.U.; Feng, J.; Wang, L.; West, R. Nicotine, carcinogen, and toxin exposure in long-term e-cigarette and nicotine replacement therapy users: A cross-sectional study. Ann. Intern. Med. 2017, 166, 390–400. [Google Scholar] [CrossRef]
- Goniewicz, M.L.; Smith, D.M.; Edwards, K.C.; Blount, B.C.; Caldwell, K.L.; Feng, J.; Wang, L.; Christensen, C.; Ambrose, B.; Borek, N.; et al. Comparison of nicotine and toxicant exposure in users of electronic cigarettes and combustible cigarettes. JAMA Netw. Open 2018, 1, e185937. [Google Scholar] [CrossRef] [PubMed]
- Steinberg, M.B.; Zimmermann, M.H.; Delnevo, C.D.; Lewis, M.J.; Shukla, P.; Coups, E.J.; Foulds, J. E-cigarette versus nicotine inhaler: Comparing the perceptions and experiences of inhaled nicotine devices. J. Gen. Intern. Med. 2014, 29, 1444–1450. [Google Scholar] [CrossRef]
- Jacobs, D.R., Jr.; Adachi, H.; Mulder, I.; Kromhout, D.; Menotti, A.; Nissinen, A.; Blackburn, H. Cigarette smoking and mortality risk: Twenty-five–year follow-up of the seven countries study. Arch. Intern. Med. 1999, 159, 733–740. [Google Scholar] [CrossRef]
- Mishra, A.; Chaturvedi, P.; Datta, S.; Sinukumar, S.; Joshi, P.; Garg, A. Harmful effects of nicotine. Indian J. Med. Paediatr. Oncol. 2015, 36, 24–31. [Google Scholar] [CrossRef] [PubMed]
- Polosa, R.; Thomson, N.C. Smoking and asthma: Dangerous liaisons. Eur. Respir. J. 2013, 41, 716–726. [Google Scholar] [CrossRef] [PubMed]
- U.S. Food and Drug Administration Center for Tobacco Products. Tobacco 21. 2025. Available online: https://www.fda.gov/tobacco-products/retail-sales-tobacco-products/tobacco-21 (accessed on 5 November 2025).
- New York State Department of Health. Current Tobacco Control Policies. 2025. Available online: https://www.health.ny.gov/prevention/tobacco_control/current_policies.htm (accessed on 5 November 2025).
- New Jersey Department of Health. Tobacco Control: Regulations and Enforcement. 2025. Available online: https://www.nj.gov/health/fhs/tobacco/regulations/ (accessed on 5 November 2025).














| Question | Reason for First Use | Reason for Current Use | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Year | 2021 | 2022 | 2023 | 2021 | 2022 | 2023 | ||||||
| Reason | Male | Female | Male | Female | Male | Female | Male | Female | Male | Female | Male | Female |
| Peer pressure | 1,397,140 (1) | 1,591,356 (1) | 1,292,926 (1) | 1,703,960 (1) | 870,112 (1) | 1,505,463 (1) | 267,091 (3) | 376,923 (3) | 267,091 (3) | 376,923 (3) | 248,057 (2) | 338,531 (2) |
| Family used | 414,410 | 543,345 | 479,423 | 698,610 | 380,707 (3) | 679,469 | 89,345 | 121,752 | 89,345 | 121,752 | 61,778 | 129,352 |
| Quit smoking | 71,919 | 59,593 | 70,024 | 40,197 | 74,515 | 42,804 | 41,456 | 32,377 | 41,456 | 32,377 | 55,222 | 38,512 |
| Costs less | 80,827 | 28,630 | 84,746 | 36,697 | 66,440 | 39,437 | 49,406 | 53,702 | 49,406 | 53,702 | 63,012 | 53,033 |
| Easier to get | 132,816 | 113,215 | 157,161 | 124,494 | 114,816 | 145,505 | 60,090 | 86,845 | 60,090 | 86,845 | 77,024 | 135,593 |
| Ads | 123,394 | 111,458 | 152,755 | 181,465 | 103,977 | 129,616 | 36,906 | 39,825 | 36,906 | 39,825 | 45,480 | 33,168 |
| Less harmful | 258,211 | 169,299 | 207,955 | 184,347 | 111,989 | 198,543 | 115,603 | 99,907 | 115,603 | 99,907 | 77,784 | 167,452 |
| Flavors | 310,477 | 385,656 | 337,139 | 456,994 | 191,949 | 367,716 | 140,517 | 194,153 | 140,517 | 194,153 | 123,598 | 195,577 |
| Can be masked | 235,357 | 321,884 | 302,860 | 367,231 | 162,583 | 305,983 | 151,638 | 222,130 | 151,638 | 222,130 | 97,039 | 196,474 |
| Do tricks | 415,138 | 434,866 | 475,772 | 475,619 | 246,441 | 396,980 | 214,816 | 260,605 | 214,816 | 260,605 | 157,083 | 238,812 |
| Curiosity | 1,191,782 (2) | 1,269,940 (2) | 1,214,240 (2) | 1,431,062 (2) | 793,400 (2) | 1,117,074 (2) | 118,738 | 194,762 | 118,738 | 194,762 | 130,084 | 124,538 |
| Anxiety | 523,571 | 769,345 (3) | 495,790 | 829,450 (3) | 281,896 | 739,950 (3) | 375,509 (2) | 678,753 (1) | 375,509 (2) | 678,753 (1) | 206,714 (3) | 571,941 (1) |
| Get high | 601,938 (3) | 604,630 | 570,619 (3) | 655,439 | 376,725 (3) | 546,496 | 455,291 (1) | 498,438 (2) | 455,291 (1) | 498,438 (2) | 262,740 (1) | 330,238 (3) |
| None above | 313,987 | 227,257 | 254,784 | 206,251 | 168,396 | 151,996 | 244,677 | 216,287 | 244,677 | 216,287 | 120,560 | 185,874 |
| Question | Reason for First Use | Reason for Current Use | ||||
|---|---|---|---|---|---|---|
| Year | 2021 | 2022 | 2023 | 2021 | 2022 | 2023 |
| Male | Peer pressure | Peer pressure | Peer pressure | Get high | Get high | Get high |
| Curiosity | Curiosity | Curiosity | Anxiety | Anxiety | Peer pressure | |
| Get high | Get high | Family used and Get high | Peer pressure | Peer pressure | Anxiety | |
| Female | Peer pressure | Peer pressure | Peer pressure | Anxiety | Anxiety | Anxiety |
| Curiosity | Curiosity | Curiosity | Get high | Get high | Peer pressure | |
| Anxiety | Anxiety | Anxiety | Peer pressure | Peer pressure | Get high | |
| Year | Df | Sum Sq | Mean Sq | F Value | Pr (>F) | ||
|---|---|---|---|---|---|---|---|
| 2021 | Sex | 1 | 2.66 × 107 | 2.66 × 107 | 0.081 | 0.78 | |
| Category | 14 | 1.03 × 1011 | 7.33 × 109 | 22.363 | 3.59 × 10−7 | *** | |
| Residuals | 14 | 4.59 × 109 | 3.28 × 108 | ||||
| 2022 | Sex | 1 | 1.66 × 109 | 1.66 × 109 | 2.761 | 0.119 | |
| Category | 14 | 1.69 × 1011 | 1.21 × 1010 | 20.168 | 7.00 × 10−7 | *** | |
| Residuals | 14 | 8.39 × 109 | 6.00 × 108 | ||||
| 2023 | Sex | 1 | 5.50 × 109 | 5.50 × 109 | 6.76 | 0.021 | * |
| Category | 14 | 1.52 × 1011 | 1.09 × 1010 | 13.37 | 9.29 × 10−6 | *** | |
| Residuals | 14 | 1.14 × 1010 | 8.13 × 108 |
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Share and Cite
Guan, T.; Yu, Z.; Bhosle, P.; Li, C.; Sun, K.; Rao, M.B. Why Our Youth Vape?—A Trend Analysis Based on Cross-Sectional Annual Surveys of Middle and High School Students in the U.S. Medicina 2026, 62, 223. https://doi.org/10.3390/medicina62010223
Guan T, Yu Z, Bhosle P, Li C, Sun K, Rao MB. Why Our Youth Vape?—A Trend Analysis Based on Cross-Sectional Annual Surveys of Middle and High School Students in the U.S. Medicina. 2026; 62(1):223. https://doi.org/10.3390/medicina62010223
Chicago/Turabian StyleGuan, Tianyuan, Zhaochong Yu, Preethi Bhosle, Chen Li, Kai Sun, and Marepalli B. Rao. 2026. "Why Our Youth Vape?—A Trend Analysis Based on Cross-Sectional Annual Surveys of Middle and High School Students in the U.S." Medicina 62, no. 1: 223. https://doi.org/10.3390/medicina62010223
APA StyleGuan, T., Yu, Z., Bhosle, P., Li, C., Sun, K., & Rao, M. B. (2026). Why Our Youth Vape?—A Trend Analysis Based on Cross-Sectional Annual Surveys of Middle and High School Students in the U.S. Medicina, 62(1), 223. https://doi.org/10.3390/medicina62010223

