Next Article in Journal
Ethical Aspects of Brain Organoid Research in News Reports: An Exploratory Descriptive Analysis
Previous Article in Journal
Treatment of Unstable Occipital Condylar Fractures in Children—A STROBE-Compliant Investigation
 
 
Article

Clinical Outcomes and Risk Factor Analysis of Patients Presenting with Emphysematous Cystitis: A 15-Year Retrospective Multicenter Study

1
Department of Urology, College of Medicine, Kyung Hee University, Seoul 02447, Korea
2
Department of Urology, Seoul Medical Center, Seoul 02053, Korea
*
Author to whom correspondence should be addressed.
Academic Editor: Giuseppe Lucarelli
Medicina 2021, 57(6), 531; https://doi.org/10.3390/medicina57060531
Received: 19 May 2021 / Accepted: 23 May 2021 / Published: 26 May 2021
(This article belongs to the Section Infectious Disease)
Background and objectives: To investigate the risk factors for emphysematous cystitis (EC) compared to those of acute cystitis (AC) to increase clinicians awareness of the possibility for the aggravation of patient status. Materials and methods: We retrospectively reviewed a total of 54 patients who were hospitalized with a diagnosis of EC by abdominal computed tomography (CT) scan from 2006 to 2020. The control group included 92 patients who were hospitalized for the treatment of AC in the same period. We sought to identify the clinical features and predisposing diseases, such as age, sex, diabetes mellitus (DM), hypertension (HTN), cerebrovascular accident (CVA), chronic kidney disease (CKD), neurogenic bladder (NB), history of urinary tract infection (UTI), and emphysematous pyelonephritis (EPN), that were associated with the development of EC. Results: The median (interquartile range (IQR)) age of the patients with EC was older than that of the patients with AC (78.5 (15.3) years (range: 52–100) vs. 70.0 (26.5) years (range: 28–97 years)). Sepsis and mortality occurred only in the EC group (48.1% and 11.1%, respectively). The univariate analysis of predisposing factors revealed that age, DM, HTN, CVA, CKD, and NB were significantly associated with EC. In the multivariate analysis, DM (OR, 6.251; 95% CI, 2.254–17.250; p < 0.001), CKD (OR, 18.439; 95% CI, 3.421–99.404; p = 0.001), NB (OR, 7.374; 95% CI, 1.993–27.285; p = 0.003) were associated with EC. Conclusions: The results of this study revealed that DM, CKD, and NB were significant risk factors for EC. The tendency toward sepsis and high mortality underscore the need for careful observation while treating patients with EC with the risk noted above. View Full-Text
Keywords: cystitis; emphysema; risk factors; sepsis; mortality cystitis; emphysema; risk factors; sepsis; mortality
Show Figures

Figure 1

MDPI and ACS Style

Choi, J.; Choi, S.-K.; Lee, S.-H.; Yoo, K.-H. Clinical Outcomes and Risk Factor Analysis of Patients Presenting with Emphysematous Cystitis: A 15-Year Retrospective Multicenter Study. Medicina 2021, 57, 531. https://doi.org/10.3390/medicina57060531

AMA Style

Choi J, Choi S-K, Lee S-H, Yoo K-H. Clinical Outcomes and Risk Factor Analysis of Patients Presenting with Emphysematous Cystitis: A 15-Year Retrospective Multicenter Study. Medicina. 2021; 57(6):531. https://doi.org/10.3390/medicina57060531

Chicago/Turabian Style

Choi, Jeonghyouk, Seung-Kwon Choi, Sang-Hyub Lee, and Koo-Han Yoo. 2021. "Clinical Outcomes and Risk Factor Analysis of Patients Presenting with Emphysematous Cystitis: A 15-Year Retrospective Multicenter Study" Medicina 57, no. 6: 531. https://doi.org/10.3390/medicina57060531

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop