Expression of Sigma-Class Glutathione-S-Transferase in Fetal and Pediatric Filum Terminale Samples: A Comparative Study
Abstract
:1. Introduction
2. Materials and Methods
Immunohistochemical Staining
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Patient No | Age | Sex | Complaints | Associated Pathology | Level of Conus Medullaris | Structure of Filum Terminale | Fibrosis | GST Expression |
---|---|---|---|---|---|---|---|---|
1 | 12 years | F | Backache, walking disturbance | Fatty filum terminale | L5 | Thick and fatty | + | + |
2 | 3 years | F | Unable to walk | Type 1 SCM+Syringomyelia | L4 | Normal | + | − |
3 | 16 years | F | Backache | Syringomyelia | L4 | Fatty | + | ++ |
4 | 16 years | M | Back pain, left leg pain | None | L4 | Normal | ++ | − |
5 | 7 months | F | Hypertrichosis, scoliosis | Type 1 SCM | L4 | Thick and fatty | + | + |
6 | 6 years | F | Walking disturbance | Previously operated for myelomeningocele | L4 | Normal | +++ | ++ |
7 | 2 years | F | Walking disturbance | Syringomyelia | L3 | Normal | + | ++ |
8 | 5 years | F | Urinary incontinence | None | L2 | Normal | + | + |
9 | 11 months | F | Walking disturbance | Type 1 SCM | L4 | Normal | + | + |
10 | 6 months | M | Motor weakness in left leg | Type 1 SCM | L4 | Normal | ++ | + |
Fetus No | Fibrosis | GST-Expression |
---|---|---|
1 | − | ++ |
2 | − | + |
3 | − | + |
4 | ++ | ++ |
5 | − | ++ |
6 | +++ | − |
7 | + | − |
8 | + | − |
9 | ++ | + |
10 | + | − |
11 | + | − |
12 | − | + |
13 | − | + |
14 | − | + |
15 | + | − |
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Kural, C.; Oguztuzun, S.; Şimşek, G.G.; Guresci, S.; Kaygın, P.; Yasar, S.; Tehli, O.; Izci, Y. Expression of Sigma-Class Glutathione-S-Transferase in Fetal and Pediatric Filum Terminale Samples: A Comparative Study. Medicina 2019, 55, 133. https://doi.org/10.3390/medicina55050133
Kural C, Oguztuzun S, Şimşek GG, Guresci S, Kaygın P, Yasar S, Tehli O, Izci Y. Expression of Sigma-Class Glutathione-S-Transferase in Fetal and Pediatric Filum Terminale Samples: A Comparative Study. Medicina. 2019; 55(5):133. https://doi.org/10.3390/medicina55050133
Chicago/Turabian StyleKural, Cahit, Serpil Oguztuzun, Gülçin Güler Şimşek, Servet Guresci, Pınar Kaygın, Soner Yasar, Ozkan Tehli, and Yusuf Izci. 2019. "Expression of Sigma-Class Glutathione-S-Transferase in Fetal and Pediatric Filum Terminale Samples: A Comparative Study" Medicina 55, no. 5: 133. https://doi.org/10.3390/medicina55050133