Applications in Which Aptamers Are Needed or Wanted in Diagnostics and Therapeutics
Abstract
:1. Introduction
2. Diagnostic Applications in Which Aptamers Are Needed or Desired
2.1. When No Commercial Antibodies Exist or Are Very Difficult to Obtain
2.2. When Antibodies Fail to Distinguish Closely Related Variant Targets
2.3. When Smaller Size Matters
3. Therapeutic Applications in Which Aptamers Are Needed or Desired
3.1. When the Target Is Too Toxic or Lethal for a Host Animal to Develop Antibodies
3.2. For Passive Immunity versus the More Expensive Humanized Monoclonal Antibodies
4. Discussion and Conclusions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Bruno, J.G. Applications in Which Aptamers Are Needed or Wanted in Diagnostics and Therapeutics. Pharmaceuticals 2022, 15, 693. https://doi.org/10.3390/ph15060693
Bruno JG. Applications in Which Aptamers Are Needed or Wanted in Diagnostics and Therapeutics. Pharmaceuticals. 2022; 15(6):693. https://doi.org/10.3390/ph15060693
Chicago/Turabian StyleBruno, John G. 2022. "Applications in Which Aptamers Are Needed or Wanted in Diagnostics and Therapeutics" Pharmaceuticals 15, no. 6: 693. https://doi.org/10.3390/ph15060693