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Periodontal Wound Healing and Tissue Regeneration: A Narrative Review

Department of Periodontology, School of Dentistry and Dental Research Institute, Seoul National University and Seoul National University Dental Hospital, Seoul 03080, Korea
Author to whom correspondence should be addressed.
Academic Editors: Yayoi Kawano, Viorica Patrulea, Mitsutoshi Sato, Olivier Jordan and Takehisa Hanawa
Pharmaceuticals 2021, 14(5), 456;
Received: 15 April 2021 / Revised: 10 May 2021 / Accepted: 11 May 2021 / Published: 12 May 2021
(This article belongs to the Special Issue Formulations for Wound Healing)
Periodontal disease is a major public health issue, and various periodontal therapies have been performed to regenerate periodontal tissues. The periodontium is a complex structure composed of specialized tissues that support the teeth, and most periodontal surgeries are invasive procedures, including a resection of the gingiva or the alveolar bone. The periodontal wound healing process is slightly different from cutaneous wound healing and is similar to fetal healing, being almost scar-free. The aim of this review article is to provide an overview of periodontal wound healing and discuss various surgical and pharmaceutical approaches to achieve stable wound healing and improve the treatment outcomes. In addition, detrimental and limiting factors that induce a compromised prognosis are discussed, along with the perspective and future direction for successful periodontal tissue regeneration. View Full-Text
Keywords: periodontium; periodontal tissue regeneration; wound healing periodontium; periodontal tissue regeneration; wound healing
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MDPI and ACS Style

Cho, Y.-D.; Kim, K.-H.; Lee, Y.-M.; Ku, Y.; Seol, Y.-J. Periodontal Wound Healing and Tissue Regeneration: A Narrative Review. Pharmaceuticals 2021, 14, 456.

AMA Style

Cho Y-D, Kim K-H, Lee Y-M, Ku Y, Seol Y-J. Periodontal Wound Healing and Tissue Regeneration: A Narrative Review. Pharmaceuticals. 2021; 14(5):456.

Chicago/Turabian Style

Cho, Young-Dan, Kyoung-Hwa Kim, Yong-Moo Lee, Young Ku, and Yang-Jo Seol. 2021. "Periodontal Wound Healing and Tissue Regeneration: A Narrative Review" Pharmaceuticals 14, no. 5: 456.

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