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Article

Ultra-Widefield Fluorescein Angiography Image Brightness Compensation Based on Geometrical Features

by
Wojciech Więcławek
1,*,
Marta Danch-Wierzchowska
1,
Marcin Rudzki
1,
Bogumiła Sędziak-Marcinek
2 and
Slawomir Jan Teper
2
1
Faculty of Biomedical Engineering, Silesian University of Technology, Roosevelta St. 40, 41-800 Zabrze, Poland
2
Clinical Department of Ophthalmology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Panewnicka St. 65, 40-760 Katowice, Poland
*
Author to whom correspondence should be addressed.
Sensors 2022, 22(1), 12; https://doi.org/10.3390/s22010012
Submission received: 26 October 2021 / Revised: 8 December 2021 / Accepted: 16 December 2021 / Published: 21 December 2021
(This article belongs to the Special Issue Innovations in Biomedical Imaging)

Abstract

Ultra-widefield fluorescein angiography (UWFA) is an emerging imaging modality used to characterise pathologies in the retinal vasculature, such as microaneurysms (MAs) and vascular leakages. Despite its potential value for diagnosis and disease screening, objective quantitative assessment of retinal pathologies by UWFA is currently limited because laborious manual processing is required. In this report, we describe a geometrical method for uneven brightness compensation inherent to UWFA imaging technique. The correction function is based on the geometrical eyeball shape, therefore it is fully automated and depends only on pixel distance from the center of the imaged retina. The method’s performance was assessed on a database containing 256 UWFA images with the use of several image quality measures that show the correction method improves image quality. The method is also compared to the commonly used CLAHE approach and was also employed in a pilot study for vascular segmentation, giving a noticeable improvement in segmentation results. Therefore, the method can be used as an image preprocessing step in retinal UWFA image analysis.
Keywords: UWFA; FA; image enhancement; gamma correction; curve length; solid angle; ophthalmology; image processing UWFA; FA; image enhancement; gamma correction; curve length; solid angle; ophthalmology; image processing

Share and Cite

MDPI and ACS Style

Więcławek, W.; Danch-Wierzchowska, M.; Rudzki, M.; Sędziak-Marcinek, B.; Teper, S.J. Ultra-Widefield Fluorescein Angiography Image Brightness Compensation Based on Geometrical Features. Sensors 2022, 22, 12. https://doi.org/10.3390/s22010012

AMA Style

Więcławek W, Danch-Wierzchowska M, Rudzki M, Sędziak-Marcinek B, Teper SJ. Ultra-Widefield Fluorescein Angiography Image Brightness Compensation Based on Geometrical Features. Sensors. 2022; 22(1):12. https://doi.org/10.3390/s22010012

Chicago/Turabian Style

Więcławek, Wojciech, Marta Danch-Wierzchowska, Marcin Rudzki, Bogumiła Sędziak-Marcinek, and Slawomir Jan Teper. 2022. "Ultra-Widefield Fluorescein Angiography Image Brightness Compensation Based on Geometrical Features" Sensors 22, no. 1: 12. https://doi.org/10.3390/s22010012

APA Style

Więcławek, W., Danch-Wierzchowska, M., Rudzki, M., Sędziak-Marcinek, B., & Teper, S. J. (2022). Ultra-Widefield Fluorescein Angiography Image Brightness Compensation Based on Geometrical Features. Sensors, 22(1), 12. https://doi.org/10.3390/s22010012

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