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Review

Biosensors as Nano-Analytical Tools for COVID-19 Detection

1
Center for Basic Sciences, Department of Chemistry, Pt. Ravishankar Shukla University, Raipur 492010, India
2
Ramrao Adik Institute of Technology, DY Patil University, Nerul, Navi Mumbai 400706, India
3
Department of Chemistry, Faculty of Science, University of Hradec Kralove, Rokitanskeho 62, 50003 Hradec Kralove, Czech Republic
4
Biomedical Research Center, University Hospital, Sokolska 581, 50005 Hradec Kralove, Czech Republic
5
School of Studies in Chemistry, Pt. Ravishankar Shukla University, Raipur 492010, India
6
Center for Basic and Applied Research, Faculty of Informatics and Management, University of Hradec Kralove, Rokitanskeho 62, 50003 Hradec Kralove, Czech Republic
*
Authors to whom correspondence should be addressed.
All three authors contributed equally.
Academic Editors: Ajeet Kaushik and Hai-Feng Ji
Sensors 2021, 21(23), 7823; https://doi.org/10.3390/s21237823
Received: 14 October 2021 / Revised: 11 November 2021 / Accepted: 18 November 2021 / Published: 24 November 2021
(This article belongs to the Special Issue Detection and Diagnosis of the New Coronavirus)
Selective, sensitive and affordable techniques to detect disease and underlying health issues have been developed recently. Biosensors as nanoanalytical tools have taken a front seat in this context. Nanotechnology-enabled progress in the health sector has aided in disease and pandemic management at a very early stage efficiently. This report reflects the state-of-the-art of nanobiosensor-based virus detection technology in terms of their detection methods, targets, limits of detection, range, sensitivity, assay time, etc. The article effectively summarizes the challenges with traditional technologies and newly emerging biosensors, including the nanotechnology-based detection kit for COVID-19; optically enhanced technology; and electrochemical, smart and wearable enabled nanobiosensors. The less explored but crucial piezoelectric nanobiosensor and the reverse transcription-loop mediated isothermal amplification (RT-LAMP)-based biosensor are also discussed here. The article could be of significance to researchers and doctors dedicated to developing potent, versatile biosensors for the rapid identification of COVID-19. This kind of report is needed for selecting suitable treatments and to avert epidemics. View Full-Text
Keywords: nanobiosensor; COVID-19 detection; optical; electrochemical; smart and wearable; piezoelectric; RT-LAMP nanobiosensor; COVID-19 detection; optical; electrochemical; smart and wearable; piezoelectric; RT-LAMP
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MDPI and ACS Style

Pradhan, A.; Lahare, P.; Sinha, P.; Singh, N.; Gupta, B.; Kuca, K.; Ghosh, K.K.; Krejcar, O. Biosensors as Nano-Analytical Tools for COVID-19 Detection. Sensors 2021, 21, 7823. https://doi.org/10.3390/s21237823

AMA Style

Pradhan A, Lahare P, Sinha P, Singh N, Gupta B, Kuca K, Ghosh KK, Krejcar O. Biosensors as Nano-Analytical Tools for COVID-19 Detection. Sensors. 2021; 21(23):7823. https://doi.org/10.3390/s21237823

Chicago/Turabian Style

Pradhan, Anchal, Preeti Lahare, Priyank Sinha, Namrata Singh, Bhanushree Gupta, Kamil Kuca, Kallol K. Ghosh, and Ondrej Krejcar. 2021. "Biosensors as Nano-Analytical Tools for COVID-19 Detection" Sensors 21, no. 23: 7823. https://doi.org/10.3390/s21237823

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