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Open AccessArticle

Nanostructured SmFeO3 Gas Sensors: Investigation of the Gas Sensing Performance Reproducibility for Colorectal Cancer Screening

1
MNF—Micro Nano Facility, Bruno Kessler Foundation, Via Sommarive 18, 38123 Trento, Italy
2
SCENT S.r.l., Via Quadrifoglio 11, 44124 Ferrara, Italy
3
Department of Physics and Earth Sciences, University of Ferrara, Via Saragat 1, 44122 Ferrara, Italy
4
INFN Section of Ferrara, Via Saragat 1/c, 44122 Ferrara, Italy
5
CNR-NANO, via G. Campi 213/a, 41125 Modena, Italy
6
Unit of Bologna, Institute for Microelectronics and Microsystems, National Research Council, via Gobetti 101, 40129 Bologna, Italy
*
Authors to whom correspondence should be addressed.
Sensors 2020, 20(20), 5910; https://doi.org/10.3390/s20205910
Received: 15 September 2020 / Revised: 13 October 2020 / Accepted: 14 October 2020 / Published: 19 October 2020
(This article belongs to the Special Issue Advanced Micro and Nano Technologies for Gas Sensing)
Among the various chemoresistive gas sensing properties studied so far, the sensing response reproducibility, i.e., the capability to reproduce a device with the same sensing performance, has been poorly investigated. However, the reproducibility of the gas sensing performance is of fundamental importance for the employment of these devices in on-field applications, and to demonstrate the reliability of the process development. This sensor property became crucial for the preparation of medical diagnostic tools, in which the use of specific chemoresistive gas sensors along with a dedicated algorithm can be used for screening diseases. In this work, the reproducibility of SmFeO3 perovskite-based gas sensors has been investigated. A set of four SmFeO3 devices, obtained from the same screen-printing deposition, have been tested in laboratory with both controlled concentrations of CO and biological fecal samples. The fecal samples tested were employed in the clinical validation protocol of a prototype for non-invasive colorectal cancer prescreening. Sensors showed a high reproducibility degree, with an error lower than 2% of the response value for the test with CO and lower than 6% for fecal samples. Finally, the reproducibility of the SmFeO3 sensor response and recovery times for fecal samples was also evaluated. View Full-Text
Keywords: nanostructured SmFeO3 perovskite; chemoresistive gas sensors; gas sensor reproducibility; CRC screening; medical diagnostic tool nanostructured SmFeO3 perovskite; chemoresistive gas sensors; gas sensor reproducibility; CRC screening; medical diagnostic tool
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MDPI and ACS Style

Gaiardo, A.; Zonta, G.; Gherardi, S.; Malagù, C.; Fabbri, B.; Valt, M.; Vanzetti, L.; Landini, N.; Casotti, D.; Cruciani, G.; Della Ciana, M.; Guidi, V. Nanostructured SmFeO3 Gas Sensors: Investigation of the Gas Sensing Performance Reproducibility for Colorectal Cancer Screening. Sensors 2020, 20, 5910. https://doi.org/10.3390/s20205910

AMA Style

Gaiardo A, Zonta G, Gherardi S, Malagù C, Fabbri B, Valt M, Vanzetti L, Landini N, Casotti D, Cruciani G, Della Ciana M, Guidi V. Nanostructured SmFeO3 Gas Sensors: Investigation of the Gas Sensing Performance Reproducibility for Colorectal Cancer Screening. Sensors. 2020; 20(20):5910. https://doi.org/10.3390/s20205910

Chicago/Turabian Style

Gaiardo, Andrea; Zonta, Giulia; Gherardi, Sandro; Malagù, Cesare; Fabbri, Barbara; Valt, Matteo; Vanzetti, Lia; Landini, Nicolò; Casotti, Davide; Cruciani, Giuseppe; Della Ciana, Michele; Guidi, Vincenzo. 2020. "Nanostructured SmFeO3 Gas Sensors: Investigation of the Gas Sensing Performance Reproducibility for Colorectal Cancer Screening" Sensors 20, no. 20: 5910. https://doi.org/10.3390/s20205910

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