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Article

Non-Enzymatic Impedimetric Sensor Based on 3-Aminophenylboronic Acid Functionalized Screen-Printed Carbon Electrode for Highly Sensitive Glucose Detection

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Department of Chemical Engineering, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais 30270-901, Brazil
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Center for Optics, Photonics and Lasers (COPL), Université Laval, Quebec City, QC G1V 0A6, Canada
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CDN Isotopes, Montreal, QC H9R 1H1, Canada
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Department of Applied Immunology, Fundação Ezequiel Dias (FUNED), Belo Horizonte, Minas Gerais 30510-010, Brazil
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Department of Chemistry, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais 30270-901, Brazil
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Institute of Chemistry, UNESP, Araraquara, São Paulo 14800-060, Brazil
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Author to whom correspondence should be addressed.
Sensors 2019, 19(7), 1686; https://doi.org/10.3390/s19071686
Received: 21 February 2019 / Revised: 5 April 2019 / Accepted: 6 April 2019 / Published: 9 April 2019
(This article belongs to the Special Issue Smart Electrochemical Screen-Printed Platforms )
A highly sensitive glucose sensor was prepared by a one-step method using 3-aminophenyl boronic acid as a unit of recognition and a screen-printed carbon electrode (SPCE) as an electrochemical transducer. Scanning Electron Microscopy confirmed the success of the functionalization of the SPCE due to the presence of clusters of boronic acid distributed on the carbon surface. In agreement with the Electrochemical Impedance Spectroscopy (EIS) tests performed before and after the functionalization, Cyclic Voltammetry results indicated that the electroactivity of the electrode decreased 37.9% owing to the presence of the poly phenylboronic acid on the electrode surface. EIS revealed that the sensor was capable to selectively detect glucose at a broad range of concentrations (limit of detection of 8.53 × 10−9 M), not recognizing fructose and sucrose. The device presented a stable impedimetric response when immediately prepared but suffered the influence of the storage time and some interfering species (dopamine, NaCl and animal serum). The response time at optimized conditions was estimated to be equal to 4.0 ± 0.6 s. View Full-Text
Keywords: sensor; glucose; Electrochemical Impedance Spectroscopy; boronic acid sensor; glucose; Electrochemical Impedance Spectroscopy; boronic acid
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MDPI and ACS Style

Dorledo de Faria, R.A.; Iden, H.; Heneine, L.G.D.; Matencio, T.; Messaddeq, Y. Non-Enzymatic Impedimetric Sensor Based on 3-Aminophenylboronic Acid Functionalized Screen-Printed Carbon Electrode for Highly Sensitive Glucose Detection. Sensors 2019, 19, 1686. https://doi.org/10.3390/s19071686

AMA Style

Dorledo de Faria RA, Iden H, Heneine LGD, Matencio T, Messaddeq Y. Non-Enzymatic Impedimetric Sensor Based on 3-Aminophenylboronic Acid Functionalized Screen-Printed Carbon Electrode for Highly Sensitive Glucose Detection. Sensors. 2019; 19(7):1686. https://doi.org/10.3390/s19071686

Chicago/Turabian Style

Dorledo de Faria, Ricardo A., Hassan Iden, Luiz G.D. Heneine, Tulio Matencio, and Younès Messaddeq. 2019. "Non-Enzymatic Impedimetric Sensor Based on 3-Aminophenylboronic Acid Functionalized Screen-Printed Carbon Electrode for Highly Sensitive Glucose Detection" Sensors 19, no. 7: 1686. https://doi.org/10.3390/s19071686

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