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Nanostructured Bismuth Film Electrode for Detection of Progesterone

Department of Analytical Chemistry, National Institute of Chemistry, Hajdrihova 19, SI-1000 Ljubljana, Slovenia
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Sensors 2018, 18(12), 4233; https://doi.org/10.3390/s18124233
Received: 6 November 2018 / Revised: 23 November 2018 / Accepted: 25 November 2018 / Published: 2 December 2018
(This article belongs to the Section Chemical Sensors)
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Abstract

Progesterone is an important hormone responsible, among others, for maintaining pregnancy via inhibition of uterus muscles activity; thus, following its concentration levels in pregnant women is of immense importance in the endeavor to prevent premature birth. In this work, the nanostructured bismuth film electrode (nsBiFE) was studied for detection of progesterone in neutral medium. Due to the ability to accumulate progesterone at the nsBiFE, the adsorptive cathodic stripping voltammetry was beneficially exploited. The nsBiFE was prepared on the surface of a glassy carbon supporting electrode and several parameters influencing the detection of progesterone were investigated. The nsBiFE exhibited superior electroanalytical characteristics in comparison to other bismuth-based electrodes and unmodified glassy carbon electrode together with satisfactory response toward low concentrations of progesterone, which are consistent with clinically significant levels. View Full-Text
Keywords: nanostructured bismuth film electrode; nsBiFE; adsorptive cathodic stripping voltammetry; progesterone; premature birth nanostructured bismuth film electrode; nsBiFE; adsorptive cathodic stripping voltammetry; progesterone; premature birth
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Zidarič, T.; Jovanovski, V.; Hočevar, S.B. Nanostructured Bismuth Film Electrode for Detection of Progesterone. Sensors 2018, 18, 4233.

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