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Sensors 2017, 17(6), 1200;

Biomechanical Modeling of Pterygium Radiation Surgery: A Retrospective Case Study

Eye Clinic Orasis, Swiss Eye Research Foundation, CH-5734 Reinach, Switzerland
Department of Physics, Faculty of Sciences, University of Novi Sad, 21000 Novi Sad, Serbia
Division of Ophthalmology, Department of Clinical Neurosciences, Geneva University Hospitals, CH-1205 Geneva, Switzerland
Faculty of Medicine of the Military Medical Academy, University of Defence, 11000 Belgrade, Serbia
Department of Radiation Oncology, Inselspital, Bern University Hospital, University of Bern, CH-3010 Bern, Switzerland
Department of Neurology, Schulthess Klinik, CH-8008 Zuerich, Switzerland
Optimo Medical, CH-2503 Biel, Switzerland
OCTlab, Department of Ophthalmology, University of Basel, CH-4001 Basel, Switzerland
Author to whom correspondence should be addressed.
Received: 31 March 2017 / Revised: 17 May 2017 / Accepted: 19 May 2017 / Published: 24 May 2017
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Pterygium is a vascularized, invasive transformation on the anterior corneal surface that can be treated by Strontium-/Yttrium90 beta irradiation. Finite element modeling was used to analyze the biomechanical effects governing the treatment, and to help understand clinically observed changes in corneal astigmatism. Results suggested that irradiation-induced pulling forces on the anterior corneal surface can cause astigmatism, as well as central corneal flattening. Finite element modeling of corneal biomechanics closely predicted the postoperative corneal surface (astigmatism error −0.01D; central curvature error −0.16D), and can help in understanding beta irradiation treatment. Numerical simulations have the potential to preoperatively predict corneal shape and function changes, and help to improve corneal treatments. View Full-Text
Keywords: pterygium; radiation; cornea surgery; biomechanics; finite element modeling; simulation pterygium; radiation; cornea surgery; biomechanics; finite element modeling; simulation

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Pajic, B.; Aebersold, D.M.; Eggspuehler, A.; Theler, F.R.; Studer, H.P. Biomechanical Modeling of Pterygium Radiation Surgery: A Retrospective Case Study. Sensors 2017, 17, 1200.

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