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Sensors 2017, 17(12), 2951; https://doi.org/10.3390/s17122951

Achievements and Prospects in Electrochemical-Based Biosensing Platforms for Aflatoxin M1 Detection in Milk and Dairy Products

1
Biotechnology Department, National Institute for Research & Development in Chemistry and Petrochemistry‚ÄĒICECHIM, 202 Spl. Independentei, Sector 6, 060021 Bucharest, Romania
2
EPI-SISTEM SRL, Bvd Brasovului 145, Sacele, 505600 Brasov, Romania
*
Authors to whom correspondence should be addressed.
Received: 15 November 2017 / Revised: 3 December 2017 / Accepted: 13 December 2017 / Published: 19 December 2017
(This article belongs to the Special Issue Protein-Based Biosensors)
Full-Text   |   PDF [1536 KB, uploaded 19 December 2017]   |  

Abstract

Aflatoxins, which are mainly produced by Aspergillus flavus and parasiticus growing on plants and products stored under inappropriate conditions, represent the most studied group of mycotoxins. Contamination of human and animal milk with aflatoxin M1, the hydroxylated metabolite of aflatoxin B1, is an important health risk factor due to its carcinogenicity and mutagenicity. Due to the low concentration of this aflatoxin in milk and milk products, the analytical methods used for its quantification have to be highly sensitive, specific and simple. This paper presents an overview of the analytical methods, especially of the electrochemical immunosensors and aptasensors, used for determination of aflatoxin M1. View Full-Text
Keywords: aflatoxin M1; immunoassays; antibody; aptamer; electrochemical biosensors aflatoxin M1; immunoassays; antibody; aptamer; electrochemical biosensors
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Gurban, A.-M.; Epure, P.; Oancea, F.; Doni, M. Achievements and Prospects in Electrochemical-Based Biosensing Platforms for Aflatoxin M1 Detection in Milk and Dairy Products. Sensors 2017, 17, 2951.

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