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Respiratory Monitoring by Porphyrin Modified Quartz Crystal Microbalance Sensors

1
Graduate School of Environmental Engineering, The University of Kitakyushu, 1-1 Hibikino, Wakamatsu, Kitakyushu 808-0135, Japan
2
Chitose Technical Center, Nihon Dempa Kogyo Co. Ltd., 1-3-1, Minami-Chitose, Hokkaido 066-0009, Japan
*
Author to whom correspondence should be addressed.
Sensors 2011, 11(1), 1177-1191; https://doi.org/10.3390/s110101177
Received: 1 December 2010 / Revised: 30 December 2010 / Accepted: 10 January 2011 / Published: 20 January 2011
(This article belongs to the Section Chemical Sensors)
A respiratory monitoring system based on a quartz crystal microbalance (QCM) sensor with a functional film was designed and investigated. Porphyrins 5,10,15,20-tetrakis-(4-sulfophenyl)-21H,23H-porphine (TSPP) and 5,10,15,20-tetrakis-(4-sulfophenyl)-21H, 23H-porphine manganese (III) chloride (MnTSPP) used as sensitive elements were assembled with a poly(diallyldimethyl ammonium chloride) (PDDA). Films were deposited on the QCM resonators using layer-by-layer method in order to develop the sensor. The developed system, in which the sensor response reflects lung movements, was able to track human respiration providing respiratory rate (RR) and respiratory pattern (RP). The sensor system was tested on healthy volunteers to compare RPs and calculate RRs. The operation principle of the proposed system is based on the fast adsorption/desorption behavior of water originated from human breath into the sensor films deposited on the QCM electrode. View Full-Text
Keywords: respiratory monitoring; quartz crystal microbalance; porphyrin based thin films; layer-by layer approach; sensor array   respiratory monitoring; quartz crystal microbalance; porphyrin based thin films; layer-by layer approach; sensor array  
MDPI and ACS Style

Selyanchyn, R.; Korposh, S.; Wakamatsu, S.; Lee, S.-W. Respiratory Monitoring by Porphyrin Modified Quartz Crystal Microbalance Sensors. Sensors 2011, 11, 1177-1191.

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