7,7-Difluoropentaphen-6(7H)-one

Round 1

Reviewer 1 Report

The manuscript “7,7-difluoropentaphen-6(7H)-” describes the synthesis of an interesting compound. The article is well written and the characterization of the compound and the discussion of the results are appropriate. I recommend the publication of the manuscript.

Author Response

Authors thank the reviewer for  the feedback.

Reviewer 2 Report

The article describes the synthesis and characterization of a new fluorinated pentaphene derivative through Diels-Alder reaction of 1,1-difluoroanthracen-2(1H)-one with o-quinodimethane generated in situ from o-bis(dibromomethyl)benzene. The product was synthesized by a method developed by the authors based on Cava procedure and isolated in moderate yield (20%).

Globally, the manuscript is well written and the introduction is adequate to the described compound. The experimental procedure is clear and the characterization data is in accordance with the synthesized compound. However, the product was obtained in moderate yield due the formation of dihalobenzocyclobutenes. The authors didn’t mention the yield of this product.

The authors should describe the yield of all products obtained in this reaction. And include some characterization data of the dihalobenzocyclobutene obtained.

Author Response

Authors thank the reviewer for the feedback.

The characteristic m/z values corresponding to dibromobenzocyclobutene obtained by GCMS were added in the text.

However since dihalobenzocyclobutenes were not the focus of this research and tetrabromo-o-xylene is added in high excess the dibromobenzocyclobutene was not isolated preparatively and the yield was not measured.