(3-Methylene-2,3-dihydronaphtho[2,3-b][1,4]dioxin-2-yl)methanol

Round 1

Reviewer 1 Report

The manuscript will be suitable for publication after the following simple revisions have been made:

Compounds 3 and 4 are known and their preparations are reported in the literature using the same reactions as in the manuscript. Articles reporting the preparation of these compounds should be cited, where applicable, indicate how the authors of the manuscript modified procedures described by other authors, as well as melting points from the literature should be cited.

In the description of the preparation of compound 5, the volume of used DMF needs to be stated.

The word concentrated is used several times. If partial evaporation of volatile components is meant, it needs to be added that the excluded solid substance has been filtered off. Otherwise, it should be said that the volatile components have been evaporated (to dryness).

In the description of the preparation of compound 6, the state and mass of the crude product should be stated.

In the description of the preparation of compound 1, the mass and concentration of the solution of used compound 6, as well as the mass of the substance 6 contained in it, should be added. The reaction time also needs to be supplemented.

By HRMS, Na⁺-adducts could be indicated, not Na-adducts. Therefore, the calculated m/z value is 251.0679 in case of compound 1 and 265.0835 in case of compound 8, respectively.

The preparation of compound 7 should also be mentioned in the section Results and Discussion.

Compound yields in percent should be rounded to whole numbers. As melting points, the temperature intervals in which substances melt must be given, with values rounded to whole degrees centigrade.

The structures of compounds 1 and 7 are well established, however, it would be good to report their infrared spectra as well.

In the reference list, some journals are listed by their full titles and some by abbreviations. This needs to be unified. I recommend using the abbreviations according to the CAS Source Index (https://cassi.cas.org/).

In ref. 8, page 442 should be supplemented.

In ref. 11, remaining authors instead of "et al." should be given.

Spelling revision is necessary, among others the first letter in the title of the article should be capitalized.

Author Response

Please see the attachment

Author Response File: Author Response.pdf