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[4-(3,4-Dimethoxyphenyl)-3,6-dimethyl-2-phenyl-3,4-dihydroquinolin-1(2H)-yl)](furan-2-yl)methanone

Laboratorio de Química Orgánica y Biomolecular, Centro de Materiales y Nanociencias (CMN), Parque Tecnológico Guatiguará, Km 2 vía Refugio, Universidad Industrial de Santander, Piedecuesta, Bucaramanga 681011, Colombia
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Academic Editor: Stefano D’Errico
Molbank 2022, 2022(3), M1413; https://doi.org/10.3390/M1413
Received: 6 July 2022 / Revised: 19 July 2022 / Accepted: 20 July 2022 / Published: 25 July 2022
A N-(2,4-diaryltetrahydroquinolin-1-yl) furan-2-carboxamide derivative, [4-(3,4-dimethoxyphenyl)-3,6-dimethyl-2-phenyl-3,4-dihydroquinolin-1(2H)-yl)](furan-2-yl)methanone, was synthesized in a two-step procedure from p-toluidine, benzaldehyde, and trans-methyl-isoeugenol as commercial starting reagents through a sequence of Povarov cycloaddition reaction/N-furoylation processes. The structure of the compound was fully characterized by IR, 1H, 13C-NMR, and X-ray diffraction data. Such types of derivatives are known as relevant therapeutic agents exhibiting potent anticancer, antibacterial, antifungal, anti-inflammatory, and immunological modulator properties. View Full-Text
Keywords: 2,6-diaryl-tetrahydroquinolines; trans-methyl-isoeugenol; green Povarov reaction; deep eutectic solvents; N-furoylation; N-(tetrahydroquinolin-1-yl) furancarboxamides 2,6-diaryl-tetrahydroquinolines; trans-methyl-isoeugenol; green Povarov reaction; deep eutectic solvents; N-furoylation; N-(tetrahydroquinolin-1-yl) furancarboxamides
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MDPI and ACS Style

Bonilla-Castañeda, S.M.; Villamizar-Mogotocoro, A.F.; Kouznetsov, V.V. [4-(3,4-Dimethoxyphenyl)-3,6-dimethyl-2-phenyl-3,4-dihydroquinolin-1(2H)-yl)](furan-2-yl)methanone. Molbank 2022, 2022, M1413. https://doi.org/10.3390/M1413

AMA Style

Bonilla-Castañeda SM, Villamizar-Mogotocoro AF, Kouznetsov VV. [4-(3,4-Dimethoxyphenyl)-3,6-dimethyl-2-phenyl-3,4-dihydroquinolin-1(2H)-yl)](furan-2-yl)methanone. Molbank. 2022; 2022(3):M1413. https://doi.org/10.3390/M1413

Chicago/Turabian Style

Bonilla-Castañeda, Sandra M., Andrés F. Villamizar-Mogotocoro, and Vladimir V. Kouznetsov. 2022. "[4-(3,4-Dimethoxyphenyl)-3,6-dimethyl-2-phenyl-3,4-dihydroquinolin-1(2H)-yl)](furan-2-yl)methanone" Molbank 2022, no. 3: M1413. https://doi.org/10.3390/M1413

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