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Short Note

3,6-Dihydro-5H-pyrazolo [4′,3′:5,6]pyrano[3,4-b]indol-5-one

Division of Pharmaceutical Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis, Zografou, 15771 Athens, Greece
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Molbank 2022, 2022(3), M1412; https://doi.org/10.3390/M1412
Received: 5 July 2022 / Revised: 16 July 2022 / Accepted: 19 July 2022 / Published: 20 July 2022
(This article belongs to the Section Organic Synthesis)
Pyrano [3,4-b]indol-1(9H)-ones and indolo [2,3-c]coumarins are important classes of heterocyclic compounds with versatile biological activities. Herein, we describe a straightforward and scalable synthesis of 3,6-dihydro-5H-pyrazolo [4′,3′:5,6]pyrano [3,4-b]indol-5-one, a pyrazolo-fused pyrano [3,4-b]indolone, via a three step approach including Fischer-indole synthesis and intramolecular esterification. The compound is fully characterized by means of 1H and 13C NMR spectra, using direct and long-range heteronuclear correlation experiments (HMBC and HMQC). View Full-Text
Keywords: pyrano [3,4-b]indol-1(9H)-ones; indolo [2,3-c]coumarins; pyrazole pyrano [3,4-b]indol-1(9H)-ones; indolo [2,3-c]coumarins; pyrazole
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MDPI and ACS Style

Kalampaliki, A.D.; Kanellopoulou, S.; Kostakis, I.K. 3,6-Dihydro-5H-pyrazolo [4′,3′:5,6]pyrano[3,4-b]indol-5-one. Molbank 2022, 2022, M1412. https://doi.org/10.3390/M1412

AMA Style

Kalampaliki AD, Kanellopoulou S, Kostakis IK. 3,6-Dihydro-5H-pyrazolo [4′,3′:5,6]pyrano[3,4-b]indol-5-one. Molbank. 2022; 2022(3):M1412. https://doi.org/10.3390/M1412

Chicago/Turabian Style

Kalampaliki, Amalia D., Sofia Kanellopoulou, and Ioannis K. Kostakis. 2022. "3,6-Dihydro-5H-pyrazolo [4′,3′:5,6]pyrano[3,4-b]indol-5-one" Molbank 2022, no. 3: M1412. https://doi.org/10.3390/M1412

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