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Synthesis and Structure Determination of 1-(4-Methoxyphenyl)-5-methyl-N’-(2-oxoindolin-3-ylidene)-1H-1,2,3-triazole-4-carbohydrazide

1
School of Chemistry, Cardiff University, Cardiff CF10 3AT, UK
2
Applied Organic Chemistry Department, Chemical Industries Research Institute, National Research Centre, Giza 12622, Egypt
3
Master of Pharmaceutical Sciences Program, California Northstate University, Elk Grove, CA 95757, USA
4
Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt
5
Cornea Research Chair, Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia
*
Author to whom correspondence should be addressed.
Academic Editor: Rodrigo Abonia
Molbank 2022, 2022(2), M1374; https://doi.org/10.3390/M1374
Received: 2 May 2022 / Revised: 25 May 2022 / Accepted: 29 May 2022 / Published: 31 May 2022
A reaction of equimolar equivalents of 1-(4-methoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carbohydrazide (1) and indoline-2,3-dione (2) in boiling ethanol for 4 h under acidic conditions gave 1-(4-methoxyphenyl)-5-methyl-N’-(2-oxoindolin-3-ylidene)-1H-1,2,3-triazole-4-carbohydrazide (3) in 88% yield. The structure of 3 was ascertained by NMR spectroscopy and single-crystal X-ray diffraction. View Full-Text
Keywords: synthesis; 1,2,3-triazole; X-ray crystal structure; heterocycles; carbohydrazide; indoline-2,3-dione synthesis; 1,2,3-triazole; X-ray crystal structure; heterocycles; carbohydrazide; indoline-2,3-dione
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MDPI and ACS Style

Kariuki, B.M.; Abdel-Wahab, B.F.; Farahat, A.A.; El-Hiti, G.A. Synthesis and Structure Determination of 1-(4-Methoxyphenyl)-5-methyl-N’-(2-oxoindolin-3-ylidene)-1H-1,2,3-triazole-4-carbohydrazide. Molbank 2022, 2022, M1374. https://doi.org/10.3390/M1374

AMA Style

Kariuki BM, Abdel-Wahab BF, Farahat AA, El-Hiti GA. Synthesis and Structure Determination of 1-(4-Methoxyphenyl)-5-methyl-N’-(2-oxoindolin-3-ylidene)-1H-1,2,3-triazole-4-carbohydrazide. Molbank. 2022; 2022(2):M1374. https://doi.org/10.3390/M1374

Chicago/Turabian Style

Kariuki, Benson M., Bakr F. Abdel-Wahab, Abdelbasset A. Farahat, and Gamal A. El-Hiti. 2022. "Synthesis and Structure Determination of 1-(4-Methoxyphenyl)-5-methyl-N’-(2-oxoindolin-3-ylidene)-1H-1,2,3-triazole-4-carbohydrazide" Molbank 2022, no. 2: M1374. https://doi.org/10.3390/M1374

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