Department of Chemistry and Biology, University of Salerno, Via Giovanni Paolo II, 84084 Fisciano (SA), Italy
Department of Physical and Chemical Sciences, University of L’Aquila, via Vetoio, 67100 Coppito (AQ), Italy
Author to whom correspondence should be addressed.
Molbank 2020, 2020(2), M1131; https://doi.org/10.3390/M1131
Received: 8 April 2020 / Revised: 4 May 2020 / Accepted: 6 May 2020 / Published: 8 May 2020
(This article belongs to the Special Issue Heterocycle Reactions)
In this work, we report a facile access to a 3,3-disubstituted isoindolinone by means of Krapcho decarboxylation reaction of the respective substituted dimethyl malonate derivative. Good isolated yields were obtained under mild reaction conditions.