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Methyl 2-(1-methyl-3-oxoisoindolin-1-yl)acetate

1
Department of Chemistry and Biology, University of Salerno, Via Giovanni Paolo II, 84084 Fisciano (SA), Italy
2
Department of Physical and Chemical Sciences, University of L’Aquila, via Vetoio, 67100 Coppito (AQ), Italy
*
Author to whom correspondence should be addressed.
Molbank 2020, 2020(2), M1131; https://doi.org/10.3390/M1131
Received: 8 April 2020 / Revised: 4 May 2020 / Accepted: 6 May 2020 / Published: 8 May 2020
(This article belongs to the Special Issue Heterocycle Reactions)
In this work, we report a facile access to a 3,3-disubstituted isoindolinone by means of Krapcho decarboxylation reaction of the respective substituted dimethyl malonate derivative. Good isolated yields were obtained under mild reaction conditions. View Full-Text
Keywords: isoindolinone; quaternary carbon; Krapcho reaction isoindolinone; quaternary carbon; Krapcho reaction
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MDPI and ACS Style

Mola, A.D.; Macchia, A.; Palombi, L.; Massa, A. Methyl 2-(1-methyl-3-oxoisoindolin-1-yl)acetate. Molbank 2020, 2020, M1131.

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