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Molbank 2018, 2018(1), M975; https://doi.org/10.3390/M975

N-(3-Chloro-2-methylphenyl)-4-(4-fluorophenyl)-1,3-thiazol-2-amine

1
Division of Biochemistry, Department of Studies in Chemistry, Mangalore University, Mangalagangothri, Mangalore 574199, Karnataka, India
2
Department of Studies in Industrial Chemistry, Mangalore University, Mangalagangothri, Mangalore 574199, Karnataka, India
3
Department of Studies in Chemistry, Mangalore University, Mangalagangothri, Mangalore 574199, Karnataka, India
*
Author to whom correspondence should be addressed.
Received: 3 January 2018 / Revised: 16 January 2018 / Accepted: 16 January 2018 / Published: 19 January 2018
(This article belongs to the Section Organic Synthesis)
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Abstract

The two precursors 3-chloro-2-methylphenylthiourea 2 and 4-fluorophenacyl bromide 4 are reacted under Hantzsch thiazole synthesis condition to yield the new compound N-(3-chloro-2-methylphenyl)-4-(4-fluorophenyl)-1,3-thiazol-2-amine 5. The IR, 1H-NMR, 13C-NMR and mass spectral data are presented, along with its in vitro antibacterial activity against Staphylococcus aureus and Chromobacterium violaceum. View Full-Text
Keywords: 3-chloro-2-methylphenylthiourea; thiazole amine; antibacterial activity 3-chloro-2-methylphenylthiourea; thiazole amine; antibacterial activity
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Uwabagira, N.; Sarojini, B.K.; Poojary, B. N-(3-Chloro-2-methylphenyl)-4-(4-fluorophenyl)-1,3-thiazol-2-amine. Molbank 2018, 2018, M975.

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