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Molbank 2017, 2017(2), M938;

4-({4-[(2E)-3-(2,5-Dimethoxyphenyl)prop-2-enoyl]phenyl}amino)-4-oxobutanoic Acid

Department of Chemistry, Faculty of Science and Technology, Airlangga University, Surabaya 60115, Indonesia
Author to whom correspondence should be addressed.
Academic Editor: Norbert Haider
Received: 14 March 2017 / Revised: 25 March 2017 / Accepted: 29 March 2017 / Published: 5 April 2017
(This article belongs to the Section Organic Synthesis)
Full-Text   |   PDF [816 KB, uploaded 5 April 2017]


A dimethoxy amide chalcone has been synthesized in a two-step reaction. First, an amine chalcone was synthesized by the reaction of 4′-aminoacetophenone and 2,5-dimethoxybenzaldehyde using 40% NaOH solution as a catalyst in ethanol, and then followed by amidation through the reaction of the formed chalcone and succinic anhydride. The structure of the target compound was established by FTIR, HR-MS, 1H- and 13C-NMR, and 2D-NMR spectral analysis. View Full-Text
Keywords: amino chalcones; amide chalcones; succinic anhydride amino chalcones; amide chalcones; succinic anhydride
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Suwito, H.; Haq, K.U.; Rahmah, N.N.D.; Kristanti, A.N.; Puspaningsih, N.N.T. 4-({4-[(2E)-3-(2,5-Dimethoxyphenyl)prop-2-enoyl]phenyl}amino)-4-oxobutanoic Acid. Molbank 2017, 2017, M938.

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