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Correction

Correction: Meinarovich et al. Diagnosis of Secondary Bacterial Meningitis via Aromatic Metabolites and Biomarkers in Cerebrospinal Fluid. Int. J. Mol. Sci. 2025, 26, 10522

by
Petr A. Meinarovich
,
Ekaterina A. Sorokina
,
Natalia V. Beloborodova
and
Alisa K. Pautova
*
Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Petrovka Str. 25-2, 107031 Moscow, Russia
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2025, 26(24), 11856; https://doi.org/10.3390/ijms262411856
Submission received: 25 November 2025 / Accepted: 1 December 2025 / Published: 9 December 2025
(This article belongs to the Section Molecular Biology)
In the original publication [1], there was a mistake in the legend for Table 2. The authors mistakenly reported erroneous reference values for 4-hydroxyphenyllactic acid (p-HPhLA), 5-hydroxyindole-3-acetic acid (5HIAA), indole-3-lactic acid (3ILA), and indole-3-acetic acid (3IAA).
This has now been corrected. We recalculated all concentrations based on the correct formula: Concentration (ng/mL)/Molar mass (g/mol) * 1000 = Concentration (nmol/L). Table 2 has also been updated accordingly. The correct Table 2 appears below.
Also, there was an error in the original publication [1] in Section 2. Results and Discussion, 2.2. Description of Cerebrospinal Fluid Samples from Cohorts #1 and #2, Paragraph Number 8. This has now been corrected. The correct paragraph appears below.
Concentrations of p-HPhLA in patients of all groups generally exceeded the normal values indicated in [26]. Concentrations of 5HIAA and 3ILA in patients without meningitis in groups 1.2 and 2.2 were generally comparable with the norm indicated in [26]. In both groups with meningitis, concentrations exceeding these values are observed. In the case of 3IAA in group 1.2, concentrations comparable to the normal values in [26] were observed.
The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.

Reference

  1. Meinarovich, P.A.; Sorokina, E.A.; Beloborodova, N.V.; Pautova, A.K. Diagnosis of Secondary Bacterial Meningitis via Aromatic Metabolites and Biomarkers in Cerebrospinal Fluid. Int. J. Mol. Sci. 2025, 26, 10522. [Google Scholar] [CrossRef] [PubMed]
Table 2. The cellular and biochemical composition and concentrations of biomarkers and aromatic metabolites in cerebrospinal fluid samples from patients with sequelae of severe brain damage with a chronic critical illness (cohort #1) and patients after neurosurgical interventions (cohort #2), and the results of comparative statistical analysis (the Wald test) between various groups of samples (statistically significant differences are highlighted in bold).
Table 2. The cellular and biochemical composition and concentrations of biomarkers and aromatic metabolites in cerebrospinal fluid samples from patients with sequelae of severe brain damage with a chronic critical illness (cohort #1) and patients after neurosurgical interventions (cohort #2), and the results of comparative statistical analysis (the Wald test) between various groups of samples (statistically significant differences are highlighted in bold).
ParameterReference ValuesCohort #1Cohort #2p Cohorts #1 and #2p 1.1 and 2.1p 1.2 and 2.2
All Samples
(n = 77)
Group 1.1 with Secondary Meningitis
(n = 21)
Group 1.2 Without Secondary Meningitis
(n = 56)
p 1.1 and 1.2All Samples
(n = 19)
Group 2.1 with Secondary Meningitis
(n = 12)
Group 2.2 Without Secondary Meningitis
(n = 7)
p 2.1 and 2.2
Leucocyte count, cells/mm32–811 (3, 96)733 (139, 2000)6 (2, 18)<0.001163 (18, 710)258 (136, 866)14 (5, 88)0.210.270.62<0.001
Lymphocytes, %90–9561 (30, 94)11 (5, 36)75 (54, 100)<0.0014 (3, 6)4 (3, 8)4 (3, 5)0.55<0.0010.08<0.001
Neutrophils, %3–547 (25, 68)84 (69, 92)40 (22, 50)<0.00188 (44, 96)96 (87, 97)37 (11, 63)<0.001<0.0010.310.57
Protein, g/L0.1–0.30.7 (0.5, 1.2)1.6 (0.6, 4.5)0.7 (0.5, 1.0)<0.0012.6 (1.2, 4.2)3.6 (2.4, 4.7)1.2 (0.5, 2.2)0.06<0.0010.360.03
Glucose, mmol/L2.8–3.93.1 (2.2, 3.8)0.6 (0.2, 3.5)3.2 (2.6, 3.8)0.122.6 (2.2, 3.5)2.2 (1.9, 2.7)3.7 (3.3, 4.2)<0.0010.420.990.78
IL-6, pg/mL1.5 (1.0, 2.2) [23]71 (10, 897)3228 (104, 5000)42 (7, 234)<0.0012336 (420, 5000)4017 (1455, 5000)271 (144, 3371)0.19<0.0010.460.03
NSE, ng/mL17.3 ± 4.6 [24]1.6 (0.9, 3.2)2.0 (1.3, 9.3)1.3 (0.7, 2.9)0.0612.1 (5.0, 37.2)20.5 (9.0, 35.7)5.0 (3.3, 64.7)0.70.140.4<0.001
S100, μg/L1.4 ± 0.5 [25] 0.8 (0.4, 3.3)3.7 (0.7, 18.0)0.6 (0.3, 1.2)<0.0016.5 (2.5, 23.1)5.5 (2.3, 26.0)9.2 (3.2, 19.6)0.98<0.0010.7<0.001
p-HPhLA, nmol/L237 (196, 319) [26]633 (370, 1246)2750 (1734, 4206)491 (281, 840)<0.001925 (533, 1485)1172 (861, 1726)522 (424, 725)0.460.70.030.1
p-HBA, nmol/Lno data33 (23, 61)35 (23, 99)32 (22, 60)0.2630 (17, 41)22 (14, 36)35 (33, 41)0.380.320.310.7
p-HPhAA, nmol/Lno data223 (101, 469)906 (362, 3167)152 (77, 278)0.03100 (60, 191)92 (66, 233)103 (60, 138)0.70.460.320.79
PhLA, nmol/Lno data67 (43, 173)538 (361, 736)52 (36, 77)<0.001100 (59, 131)108 (94, 145)47 (35, 68)0.260.570.160.43
5HIAA, nmol/L71 (55, 102) [26]112 (22, 224)162 (85, 306)72 (<20, 212)0.35122 (81, 204)143 (103, 215)72 (62, 146)0.910.870.770.93
3ILA, nmol/L9 (7–12) [26]11 (4, 27)202 (22, 472)5 (3, 15)<0.00125 (18, 85)60 (25, 93)10 (6, 18)0.390.950.260.03
3ICA, nmol/Lno data11 (6, 14)12 (11, 20)8 (6, 13)0.038 (6, 10)8 (7, 11)5 (4, 9)0.70.470.170.38
3IAA, nmol/L20 (14–32) [26]39 (22, 79)96 (47, 204)26 (18, 44)0.1271 (43, 118)73 (65, 88)47 (35, 177)0.470.140.60.03
3IPA, nmol/L0.11 ± 0.02
[10]
<2 (<2, 4)2 (<2, 4)<2 (<2, 4)<0.0019 (3, 15)9 (4, 16)2 (<2, 14)0.560.270.88<0.001
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MDPI and ACS Style

Meinarovich, P.A.; Sorokina, E.A.; Beloborodova, N.V.; Pautova, A.K. Correction: Meinarovich et al. Diagnosis of Secondary Bacterial Meningitis via Aromatic Metabolites and Biomarkers in Cerebrospinal Fluid. Int. J. Mol. Sci. 2025, 26, 10522. Int. J. Mol. Sci. 2025, 26, 11856. https://doi.org/10.3390/ijms262411856

AMA Style

Meinarovich PA, Sorokina EA, Beloborodova NV, Pautova AK. Correction: Meinarovich et al. Diagnosis of Secondary Bacterial Meningitis via Aromatic Metabolites and Biomarkers in Cerebrospinal Fluid. Int. J. Mol. Sci. 2025, 26, 10522. International Journal of Molecular Sciences. 2025; 26(24):11856. https://doi.org/10.3390/ijms262411856

Chicago/Turabian Style

Meinarovich, Petr A., Ekaterina A. Sorokina, Natalia V. Beloborodova, and Alisa K. Pautova. 2025. "Correction: Meinarovich et al. Diagnosis of Secondary Bacterial Meningitis via Aromatic Metabolites and Biomarkers in Cerebrospinal Fluid. Int. J. Mol. Sci. 2025, 26, 10522" International Journal of Molecular Sciences 26, no. 24: 11856. https://doi.org/10.3390/ijms262411856

APA Style

Meinarovich, P. A., Sorokina, E. A., Beloborodova, N. V., & Pautova, A. K. (2025). Correction: Meinarovich et al. Diagnosis of Secondary Bacterial Meningitis via Aromatic Metabolites and Biomarkers in Cerebrospinal Fluid. Int. J. Mol. Sci. 2025, 26, 10522. International Journal of Molecular Sciences, 26(24), 11856. https://doi.org/10.3390/ijms262411856

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