Is Radiographic Aftercare Obsolete? How Testing Positive for ctDNA Can Be a Precedent for Late Relapse, Even in Low-Risk Hormone-Receptor-Positive Breast Cancer
Abstract
1. Introduction
2. Results
3. Discussion
4. Materials and Methods
- RaDaR panel design
- b.
- Plasma ctDNA test
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
AI | Aromatase inhibitor |
CTC | Circulating tumor cells |
ctDNA | Circulating free tumor DNA |
CT scan | Computer tomography scan |
eBC | Early breast cancer |
ER | Estrogen receptor |
MRD | Molecular residual disease |
PgR | Progesterone receptor |
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Pfister, K.; Huesmann, S.; Fink, A.; Friedl, T.W.P.; Mergel, F.; Schäffler, H.P.; Hartkopf, A.; Lukac, S.; Veselinovic, K.; Mehmeti, F.; et al. Is Radiographic Aftercare Obsolete? How Testing Positive for ctDNA Can Be a Precedent for Late Relapse, Even in Low-Risk Hormone-Receptor-Positive Breast Cancer. Int. J. Mol. Sci. 2025, 26, 8498. https://doi.org/10.3390/ijms26178498
Pfister K, Huesmann S, Fink A, Friedl TWP, Mergel F, Schäffler HP, Hartkopf A, Lukac S, Veselinovic K, Mehmeti F, et al. Is Radiographic Aftercare Obsolete? How Testing Positive for ctDNA Can Be a Precedent for Late Relapse, Even in Low-Risk Hormone-Receptor-Positive Breast Cancer. International Journal of Molecular Sciences. 2025; 26(17):8498. https://doi.org/10.3390/ijms26178498
Chicago/Turabian StylePfister, Kerstin, Sophia Huesmann, Angelina Fink, Thomas W. P. Friedl, Franziska Mergel, Henning P. Schäffler, Andreas Hartkopf, Stefan Lukac, Kristina Veselinovic, Forca Mehmeti, and et al. 2025. "Is Radiographic Aftercare Obsolete? How Testing Positive for ctDNA Can Be a Precedent for Late Relapse, Even in Low-Risk Hormone-Receptor-Positive Breast Cancer" International Journal of Molecular Sciences 26, no. 17: 8498. https://doi.org/10.3390/ijms26178498
APA StylePfister, K., Huesmann, S., Fink, A., Friedl, T. W. P., Mergel, F., Schäffler, H. P., Hartkopf, A., Lukac, S., Veselinovic, K., Mehmeti, F., Campbell, N., Pipinikas, C., Deininger, K., Beer, A., Lorenz, S., Beer, M., Wiesmüller, L., Janni, W., Heublein, S., & Rack, B. (2025). Is Radiographic Aftercare Obsolete? How Testing Positive for ctDNA Can Be a Precedent for Late Relapse, Even in Low-Risk Hormone-Receptor-Positive Breast Cancer. International Journal of Molecular Sciences, 26(17), 8498. https://doi.org/10.3390/ijms26178498