Life-Threatening Macrophage Activation Syndrome in Pregnancy: First Manifestation of SLE Induced by Parvovirus B19
Abstract
1. Introduction
2. Case Report
3. Discussion
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Analysis | On Admission | Before CS Therapy | After 6th CYC Pulse | Reference Range | |
---|---|---|---|---|---|
Complete blood count | WBC | 2.9 | 2.8 | 4.3 | 3.4–9.7 × 109/L |
th | 2.3 | 2.2 | 2.5 | 2.1–6.5 × 109/L | |
Ly | 0.4 | 0.05 | 1.2 | 1.2–3.4 × 109/L | |
RBC | 3.26 | 3.22 | 3.95 | 3.86–5.08 × 1012/L | |
Hb | 92 | 82 | 114 | 119–157 g/L | |
PLT | 259 | 113 | 277 | 150–450 × 109/L | |
Markers of inflammation | ESR | - | 100 | 42 | <10 mm/h |
CRP | 51.7 | 55.5 | 10.3 | <5 mg/L | |
Ferritin | 1262.3 | 1648.3 | 163.5 | 4.6–204 µg/L | |
Liver function | AST | 145 | 189 | 47 | <37 U/L |
ALT | 85 | 91 | 74 | <41 U/L | |
GGT | 277 | 255 | 113 | <38 U/L | |
ALP | 342 | - | 98 | 40–120 U/L | |
TGs | - | 2.11 | 1.92 | 0–1.7 mmol/L | |
Kidney function | Urea | 1.9 | 2.1 | 4.7 | 2.5–7.5 mmol/L |
Creatinine | 40 | 41 | 60 | 45–84 umol/L | |
eGFR | >60 | >60 | >60 | >60 mL/min/ 1.73 m2 | |
Urine sediment | - | Erythrocytes leucocytes | Proteins, hemoglobin erythrocyte leucocytes | - | |
24 h-proteiuria (g/24 h) | - | 2.03 | 3.83 | <0.5 g/day |
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Plavsic, A.; Miskovic, R.; Jovanovic, D.; Karic, U.; Jovicic, Z.; Radovic, S.; Drazic, A.; Dasic, A.; Arandjelovic, S. Life-Threatening Macrophage Activation Syndrome in Pregnancy: First Manifestation of SLE Induced by Parvovirus B19. Int. J. Mol. Sci. 2025, 26, 5406. https://doi.org/10.3390/ijms26115406
Plavsic A, Miskovic R, Jovanovic D, Karic U, Jovicic Z, Radovic S, Drazic A, Dasic A, Arandjelovic S. Life-Threatening Macrophage Activation Syndrome in Pregnancy: First Manifestation of SLE Induced by Parvovirus B19. International Journal of Molecular Sciences. 2025; 26(11):5406. https://doi.org/10.3390/ijms26115406
Chicago/Turabian StylePlavsic, Aleksandra, Rada Miskovic, Dragana Jovanovic, Uros Karic, Zikica Jovicic, Sara Radovic, Ana Drazic, Aleksandra Dasic, and Snezana Arandjelovic. 2025. "Life-Threatening Macrophage Activation Syndrome in Pregnancy: First Manifestation of SLE Induced by Parvovirus B19" International Journal of Molecular Sciences 26, no. 11: 5406. https://doi.org/10.3390/ijms26115406
APA StylePlavsic, A., Miskovic, R., Jovanovic, D., Karic, U., Jovicic, Z., Radovic, S., Drazic, A., Dasic, A., & Arandjelovic, S. (2025). Life-Threatening Macrophage Activation Syndrome in Pregnancy: First Manifestation of SLE Induced by Parvovirus B19. International Journal of Molecular Sciences, 26(11), 5406. https://doi.org/10.3390/ijms26115406