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Volume 24
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Review

MicroRNAs in the Mouse Developing Retina

by
Jorge Navarro-Calvo
1,
Gema Esquiva
2,
Violeta Gómez-Vicente
2 and
Luis M. Valor
1,*
1
Unidad de Investigación, Hospital General Universitario Dr. Balmis, ISABIAL, 03010 Alicante, Spain
2
Department of Optics, Pharmacology and Anatomy, University of Alicante, 03690 Alicante, Spain
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2023, 24(3), 2992; https://doi.org/10.3390/ijms24032992
Submission received: 15 December 2022 / Revised: 23 January 2023 / Accepted: 30 January 2023 / Published: 3 February 2023
(This article belongs to the Special Issue Noncoding RNAs in Regulatory Circuitries Underlying Neuronal Differentiation, Function and Disease)
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Abstract

The retina is among the highest organized tissues of the central nervous system. To achieve such organization, a finely tuned regulation of developmental processes is required to form the retinal layers that contain the specialized neurons and supporting glial cells to allow precise phototransduction. MicroRNAs are a class of small RNAs with undoubtful roles in fundamental biological processes, including neurodevelopment of the brain and the retina. This review provides a short overview of the most important findings regarding microRNAs in the regulation of retinal development, from the developmental-dependent rearrangement of the microRNA expression program to the key roles of particular microRNAs in the differentiation and maintenance of retinal cell subtypes.
Keywords: retina; mouse; Dicer; miR-183/96/182; miR-204/211; miR-124; miR-9; let-7; transcriptomics retina; mouse; Dicer; miR-183/96/182; miR-204/211; miR-124; miR-9; let-7; transcriptomics

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MDPI and ACS Style

Navarro-Calvo, J.; Esquiva, G.; Gómez-Vicente, V.; Valor, L.M. MicroRNAs in the Mouse Developing Retina. Int. J. Mol. Sci. 2023, 24, 2992. https://doi.org/10.3390/ijms24032992

AMA Style

Navarro-Calvo J, Esquiva G, Gómez-Vicente V, Valor LM. MicroRNAs in the Mouse Developing Retina. International Journal of Molecular Sciences. 2023; 24(3):2992. https://doi.org/10.3390/ijms24032992

Chicago/Turabian Style

Navarro-Calvo, Jorge, Gema Esquiva, Violeta Gómez-Vicente, and Luis M. Valor. 2023. "MicroRNAs in the Mouse Developing Retina" International Journal of Molecular Sciences 24, no. 3: 2992. https://doi.org/10.3390/ijms24032992

APA Style

Navarro-Calvo, J., Esquiva, G., Gómez-Vicente, V., & Valor, L. M. (2023). MicroRNAs in the Mouse Developing Retina. International Journal of Molecular Sciences, 24(3), 2992. https://doi.org/10.3390/ijms24032992

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