Differential Interventional Effects of Omega-6 and Omega-3 Polyunsaturated Fatty Acids on High Fat Diet-Induced Obesity and Hepatic Pathology
Abstract
:1. Introduction
2. Results
2.1. The Differential Effects of a High-Fat Diet Rich in n-6 PUFAs or n-3 PUFAs on Obesity
2.2. The Differential Effects of High-Fat Diet Rich in n-6 PUFAs or n-3 PUFAs on Glucose Homeostasis
2.3. The Differential Effects of a High-Fat Diet Rich in n-6 PUFAs or n-3 PUFAs on the Hepatic Pathology
2.4. The Differential Effects of High-Fat Diet Rich in n-6 PUFAs or n-3 PUFAs on mRNA Levels of Lipogenic Enzymes in the Liver
3. Discussion
4. Materials and Methods
4.1. Diets
4.2. Animals
4.3. Body Composition
4.4. Glucose Tolerance Test (GTT) and Insulin Tolerance Test (ITT)
4.5. Semi-Quantitative PCR Analysis
4.6. Histology
4.7. Hepatic Triglyceride Measurement
4.8. Fatty Acid Profile
4.9. Statistical Analysis
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Hao, L.; Chen, C.-Y.; Nie, Y.-H.; Kaliannan, K.; Kang, J.X. Differential Interventional Effects of Omega-6 and Omega-3 Polyunsaturated Fatty Acids on High Fat Diet-Induced Obesity and Hepatic Pathology. Int. J. Mol. Sci. 2023, 24, 17261. https://doi.org/10.3390/ijms242417261
Hao L, Chen C-Y, Nie Y-H, Kaliannan K, Kang JX. Differential Interventional Effects of Omega-6 and Omega-3 Polyunsaturated Fatty Acids on High Fat Diet-Induced Obesity and Hepatic Pathology. International Journal of Molecular Sciences. 2023; 24(24):17261. https://doi.org/10.3390/ijms242417261
Chicago/Turabian StyleHao, Lei, Chih-Yu Chen, Yong-Hui Nie, Kanakaraju Kaliannan, and Jing X. Kang. 2023. "Differential Interventional Effects of Omega-6 and Omega-3 Polyunsaturated Fatty Acids on High Fat Diet-Induced Obesity and Hepatic Pathology" International Journal of Molecular Sciences 24, no. 24: 17261. https://doi.org/10.3390/ijms242417261