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Volume 24
Issue 14
10.3390/ijms241411708
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Review
Peer-Review Record

Antibiotic Resistance, Susceptibility Testing and Stewardship in Helicobacter pylori Infection

Int. J. Mol. Sci. 2023, 24(14), 11708; https://doi.org/10.3390/ijms241411708
by Ho-Yu Ng 1, Wai K. Leung 2,* and Ka-Shing Cheung 2,3,*
Reviewer 1:
Deepa Kuttappan
Reviewer 2:
Arshad Farid
Reviewer 3: Anonymous
Int. J. Mol. Sci. 2023, 24(14), 11708; https://doi.org/10.3390/ijms241411708
Submission received: 21 June 2023 / Revised: 12 July 2023 / Accepted: 17 July 2023 / Published: 20 July 2023
(This article belongs to the Special Issue Helicobacter pylori Cell Biology and Pathogenesis)

Round 1

Reviewer 1 Report

1. In Table 1: It will be better to include reference for each resistance mechanism mentioned

2. For better clarity, it will be good to add subheadings to Antibiotic stewardship section

3. Topic selection and general organization of the paper is excellent

4. If possible, reduce / streamline the information in the tables

Only minor edits needed.

Line 181- use 'except' in place of 'expect'

 

 

Author Response

Please see the attachment.

Author Response File: Author Response.docx

Reviewer 2 Report

1)      The abstract section should be updated with an emphasis on the problem statement and novelty of the work.

2)      The introduction section requires improvement because it is so brief. It should compile critical findings from the preceding studies and highlight the research gaps that motivate authors to carry on with this study.

3)      I think at least 2-3 figures should be added in the paper because figures are the beauty of a review paper to describe the whole materials/procedure/process, some interesting self based figures (with own idea) should be added to desceibe the whole process.

4)      How can we raise public awareness for antibiotic resistance?

5)      How can healthcare providers help prevent the spread of antibiotic resistance? What are ways that patients can prevent antibiotic resistance in healthcare settings?

6)      Discus the limitations and the strengths of this study.

7)      The conclusion section is not enough and needs to be upgraded.

Nil

Author Response

Please see the attachment.

Author Response File: Author Response.docx

Reviewer 3 Report

In this study, the authors gave an overview of the current H. pylori antibiotic resistance patterns and mechanisms as well as different antibiotic susceptibility testing methods that are currently in use.
You have no keywords. Please add them.
You did not specify what type of study it is. Please add this information.
Please explain all abbreviations that appear in the article (eg AST).
The 4 tables are clear.
The article presents 158 references, being up to date. In my opinion, the 7 self-citations you used are too many. I recommend you to reduce their number.

Author Response

Please see the attachment.

Author Response File: Author Response.docx

Round 2

Reviewer 2 Report

I have critically and carefully evaluated this paper and the authors gave careful consideration to every comment. The paper is now suitable for publication. 

NA

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