A State-of-Art Review of the Vicious Circle of Sleep Disorders, Diabetes and Neurodegeneration Involving Metabolism and Microbiota Alterations
Abstract
:1. Introduction
2. Methods
3. Results
3.1. Dementia and Sleep: Common Mechanisms
3.2. Dementia and Metabolism: Common Mechanisms
3.2.1. Insulin Resistance and Genetic Variability
3.2.2. Hormonal Disruption
3.2.3. Gut Microbiota
3.3. Sleep and Metabolism: Common Mechanisms
3.3.1. OSAS, Insulin Resistance, and Hormonal Disruption
3.3.2. Circadian Rhythm and Clock Genes
3.3.3. Gut Microbiota
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Versace, S.; Pellitteri, G.; Sperotto, R.; Tartaglia, S.; Da Porto, A.; Catena, C.; Gigli, G.L.; Cavarape, A.; Valente, M. A State-of-Art Review of the Vicious Circle of Sleep Disorders, Diabetes and Neurodegeneration Involving Metabolism and Microbiota Alterations. Int. J. Mol. Sci. 2023, 24, 10615. https://doi.org/10.3390/ijms241310615
Versace S, Pellitteri G, Sperotto R, Tartaglia S, Da Porto A, Catena C, Gigli GL, Cavarape A, Valente M. A State-of-Art Review of the Vicious Circle of Sleep Disorders, Diabetes and Neurodegeneration Involving Metabolism and Microbiota Alterations. International Journal of Molecular Sciences. 2023; 24(13):10615. https://doi.org/10.3390/ijms241310615
Chicago/Turabian StyleVersace, Salvatore, Gaia Pellitteri, Roberto Sperotto, Sara Tartaglia, Andrea Da Porto, Cristiana Catena, Gian Luigi Gigli, Alessandro Cavarape, and Mariarosaria Valente. 2023. "A State-of-Art Review of the Vicious Circle of Sleep Disorders, Diabetes and Neurodegeneration Involving Metabolism and Microbiota Alterations" International Journal of Molecular Sciences 24, no. 13: 10615. https://doi.org/10.3390/ijms241310615