Arrhythmias after COVID-19 Vaccination: Have We Left All Stones Unturned?
Abstract
:1. Introduction
2. Data from the Literature and Vigilance Databases
Authors | Title | Year | N. of Cases | Centre/Nation | Type of Vaccine | Type of Arrhythmia |
---|---|---|---|---|---|---|
Aiba T et al. [5] | “Frequent Premature Ventricular Contraction and Non-Sustained Ventricular Tachycardia After the SARS-CoV-2 Vaccination in Patient with Implantable Cardioverter Defibrillator Due to Acquired Long-QT Syndrome” | June 2021 | 1 | Japan | Pfizer-BioNTech | Premature ventricular contraction and non-sustained polymorphic ventricular tachycardia |
Abrich and Olshansky [6] | “Torsades de pointes following vaccination for COVID-19” | June 2022 | 1 | USA | Pfizer-BioNTech | Torsades de pointes-ventricular fibrillation |
Beccarino et al. [7] | “COVID-19 vaccination associated right ventricular outflow tract ventricular tachycardia in a structurally normal heart” | March 2022 | 1 | USA | Pfizer-BioNTech | Sustained unstable ventricular tachycardia |
Slater et al. [8] | “VT storm in long QT resulting from COVID-19 vaccine allergy treated with epinephrine” | November 2021 | 1 | Canada | Moderna | Ventricular tachycardia storm in long QT |
M. Teresa Marco García et al. [9] | “Tachycardia as an undescribed adverse effect to the Comirnaty© vaccine (BNT162b2 Pfizer-BioNTech COVID-19 vaccine): Description of 3 cases with a history of SARS-CoV-2 disease” | May 2022 | 3 | Spain | Pfizer-BioNTech | Ventricular Tachycardia and extrasystoles in physicians |
Hoffer Etienne et al. [10] | “Transient but recurrent complete heart block in a patient after COVID-19 vaccination—A case report” | April 2022 | 1 | Belgium | Pfizer-BioNTech | Transient but recurrent complete heart block |
Kyung Hee Lim and Jong-Sung Park [17] | COVID-19 Vaccination-Induced Ventricular Fibrillation in an Afebrile Patient with Brugada Syndrome | April 2022 | 1 | Korea | Pfizer-BioNTech | Ventricular fibrillation |
3. The Molecular Pathway behind the Heart Electrophysiology Alteration
4. Conclusions
Author Contributions
Funding
Informed Consent Statement
Conflicts of Interest
References
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Cocco, N.; Leibundgut, G.; Pelliccia, F.; Cammalleri, V.; Nusca, A.; Mangiacapra, F.; Cocco, G.; Fanale, V.; Ussia, G.P.; Grigioni, F. Arrhythmias after COVID-19 Vaccination: Have We Left All Stones Unturned? Int. J. Mol. Sci. 2023, 24, 10405. https://doi.org/10.3390/ijms241210405
Cocco N, Leibundgut G, Pelliccia F, Cammalleri V, Nusca A, Mangiacapra F, Cocco G, Fanale V, Ussia GP, Grigioni F. Arrhythmias after COVID-19 Vaccination: Have We Left All Stones Unturned? International Journal of Molecular Sciences. 2023; 24(12):10405. https://doi.org/10.3390/ijms241210405
Chicago/Turabian StyleCocco, Nino, Gregor Leibundgut, Francesco Pelliccia, Valeria Cammalleri, Annunziata Nusca, Fabio Mangiacapra, Giulio Cocco, Valerio Fanale, Gian Paolo Ussia, and Francesco Grigioni. 2023. "Arrhythmias after COVID-19 Vaccination: Have We Left All Stones Unturned?" International Journal of Molecular Sciences 24, no. 12: 10405. https://doi.org/10.3390/ijms241210405