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Review

Curcumin in Retinal Diseases: A Comprehensive Review from Bench to Bedside

1
Eye Center, Humanitas Gavazzeni-Castelli, 24128 Bergamo, Italy
2
Department of Biomedical Sciences, Humanitas University, 20100 Milano, Italy
3
Optometry and Visual Sciences Department, University of London, London WC1E 7HU, UK
*
Author to whom correspondence should be addressed.
Academic Editors: Jérôme Roy and Nobuyuki Takahashi
Int. J. Mol. Sci. 2022, 23(7), 3557; https://doi.org/10.3390/ijms23073557
Received: 21 January 2022 / Revised: 20 March 2022 / Accepted: 22 March 2022 / Published: 24 March 2022
(This article belongs to the Special Issue Nutrition and Metabolism in Health and Disease: From Gene to Organism)
Recent evidence in basic science is leading to a growing interest in the possible role of curcumin in treating retinal diseases. Curcumin has been demonstrated to be able to modulate gene transcription and reduce ganglion cell apoptosis, downgrade VEGF, modulate glucose levels and decrease vascular dysfunction. So far, the use of curcumin has been limited by poor bioavailability; to overcome this issue, different types of carriers have been used. Multiple recent studies disclosed the efficacy of using curcumin in treating different retinal conditions. The aim of this review is to comprehensively review and discuss the role of curcumin in retinal diseases from bench to bedside. View Full-Text
Keywords: curcumin; review; carrier; diabetic retinopathy; retinitis pigmentosa; macular degeneration curcumin; review; carrier; diabetic retinopathy; retinitis pigmentosa; macular degeneration
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MDPI and ACS Style

Allegrini, D.; Raimondi, R.; Borgia, A.; Sorrentino, T.; Montesano, G.; Tsoutsanis, P.; Cancian, G.; Verma, Y.; De Rosa, F.P.; Romano, M.R. Curcumin in Retinal Diseases: A Comprehensive Review from Bench to Bedside. Int. J. Mol. Sci. 2022, 23, 3557. https://doi.org/10.3390/ijms23073557

AMA Style

Allegrini D, Raimondi R, Borgia A, Sorrentino T, Montesano G, Tsoutsanis P, Cancian G, Verma Y, De Rosa FP, Romano MR. Curcumin in Retinal Diseases: A Comprehensive Review from Bench to Bedside. International Journal of Molecular Sciences. 2022; 23(7):3557. https://doi.org/10.3390/ijms23073557

Chicago/Turabian Style

Allegrini, Davide, Raffaele Raimondi, Alfredo Borgia, Tania Sorrentino, Giovanni Montesano, Panos Tsoutsanis, Giuseppe Cancian, Yash Verma, Francesco Paolo De Rosa, and Mario R. Romano. 2022. "Curcumin in Retinal Diseases: A Comprehensive Review from Bench to Bedside" International Journal of Molecular Sciences 23, no. 7: 3557. https://doi.org/10.3390/ijms23073557

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