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Review
Peer-Review Record

Using Exogenous Melatonin, Glutathione, Proline, and Glycine Betaine Treatments to Combat Abiotic Stresses in Crops

Int. J. Mol. Sci. 2022, 23(21), 12913; https://doi.org/10.3390/ijms232112913
by Memoona Khalid 1, Hafiz Mamoon Rehman 1,2,*, Nisar Ahmed 1, Sehar Nawaz 1, Fozia Saleem 1, Shakeel Ahmad 3, Muhammad Uzair 4, Iqrar Ahmad Rana 1,5, Rana Muhammad Atif 5, Qamar U. Zaman 5 and Hon-Ming Lam 2,*
Reviewer 1:
Reviewer 2:
Int. J. Mol. Sci. 2022, 23(21), 12913; https://doi.org/10.3390/ijms232112913
Submission received: 20 September 2022 / Revised: 14 October 2022 / Accepted: 19 October 2022 / Published: 26 October 2022

Round 1

Reviewer 1 Report

the paper entitled 'Using Exogenous Melatonin, Glutathione, Proline and Glycine Betaine Treatments to Combat Abiotic Stresses in Crops' by Khalid et al. is dealing with an imprtant topic. Nevertheless, I have some recommendations and comments (attached in the PDF) to improve the quality of this content.

1/Abstract: this section should be improved by inserting some conclusions and constatation

2/Introduction: This section should clearly state what has been achieved and what will be added to the part of knowledge regarding the topic of the paper

3/ The rest of the paper should consider the comments and mistakes highlighted directly in the attached file while editing the manuscript and try in every section to give explanation and conclusion to the treated part of bibliographical research by the authors

I recommend also the author (If possible of course) to think about a classification according to the dose of treatment for glutathione, proline etc or by crop type of course if author notuced such a variation and dependence.

  I have attached many comments attached

Comments for author File: Comments.pdf

Author Response

Comment#1 Abstract: this section should be improved by inserting some conclusions and constatation

Answer#1 Conclusions added as suggested (lines 27-30).

 

Comment#2 Introduction: This section should clearly state what has been achieved and what will be added to the part of knowledge regarding the topic of the paper

Answer#2 Revised accordingly (lines 79-83).

  

Comment#3 The rest of the paper should consider the comments and mistakes highlighted directly in the attached file while editing the manuscript and try in every section to give explanation and conclusion to the treated part of bibliographical research by the authors

Answer#3 Revised accordingly (highlighted in the revised manuscript).

  

Comment#4 I recommend also the author (If possible of course) to think about a classification according to the dose of treatment for glutathione, proline etc or by crop type of course if author notuced such a variation and dependence.

I have attached many comments attached

Answer#4 Revised accordingly as much as possible (highlighted in the revised manuscript).

Reviewer 2 Report

The review of “Using Exogenous Melatonin, Glutathione, Proline and Glycine Betaine Treatments to Combat Abiotic Stresses in Crops” well summarized the various protection effects and related applications of four small-molecular antioxidants against abiotic stresses (drought, salinity, heat, cold, and heavy metal stress). The manuscript was well prepared except some minimum issues.

 

1. lines 11-28, the abstract may not just simply list various protection effects of four compounds. A more compact and comprehensive viewpoint extracted from the manuscript is recommended for the content of abstract, which can be more enlightened and attractive for the readerships.

 

2. Lines 78-79,

(1) the resolution of two figures here is too low. The clearer (or original) ones may be used to replace them.

(2) what is the caption or title for the figure in page 3?

 

 3. Please unify the color and clean the revision records in the main text. The font size in the tables may be adjusted for some unfitted content, such as tables 8, 12 and 18. 

 

 4. The format of references may be unified. (keeping DOI or not?)

Author Response

Comment#1 lines 11-28, the abstract may not just simply list various protection effects of four compounds. A more compact and comprehensive viewpoint extracted from the manuscript is recommended for the content of abstract, which can be more enlightened and attractive for the readerships.

Answer#1 Conclusion are added accordingly (lines 27-30).

 

Comment#2 Lines 78-79,

  • the resolution of two figures here is too low. The clearer (or original) ones may be used to replace them.

 Improved accordingly.

  • what is the caption or title for the figure in page 3?

Title added (line 88).

 

Comment#3 Please unify the color and clean the revision records in the main text. The font size in the tables may be adjusted for some unfitted content, such as tables 8, 12 and 18. 

Answer#3 Done accordingly.

 

Comment#4 The format of references may be unified. ( keeping DOI or not?)

Answer#4 Done accordingly.

Round 2

Reviewer 1 Report

I have noticed a susbstantial revision made to the manuscript

I recommend the publication of the manuscript at this stage.

 

 

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