In the original publication [
1], there was a mistake in
Table 2 and
Table 3 as published. In the
p-value column, a minus sign was missing at the exponent. The corrected
Table 2 and
Table 3 appear below. The authors apologize for any inconvenience caused and state that the results and scientific conclusions are unaffected by these changes. The original publication has also been updated.
Table 2.
Diseases or Functions Annotation from IPA Core Analysis on given gene datasets. The top 10 most significant annotations are shown.
Table 3.
Diseases or Functions Annotations in common between methylation-profiling microarray data and targeted methylation sequencing data (data from IPA Core Analysis).
Reference
- Rondinone, O.; Murgia, A.; Costanza, J.; Tabano, S.; Camanni, M.; Corsaro, L.; Fontana, L.; Colapietro, P.; Calzari, L.; Motta, S.; et al. Extensive Placental Methylation Profiling in Normal Pregnancies. Int. J. Mol. Sci. 2021, 22, 2136. [Google Scholar] [CrossRef] [PubMed]
Table 2.
Diseases or Functions Annotation from IPA Core Analysis on given gene datasets. The top 10 most significant annotations are shown.
| A |
| Diseases or Functions Annotation | p-Value |
| Leukocyte migration | 1.52 × 10−16 |
| Cell movement of lymphocytes | 5.05 × 10−14 |
| Cell movement of mononuclear leukocytes | 6.30 × 10−14 |
| Quantity of leukocytes | 7.50 × 10−14 |
| Lymphocyte migration | 9.59 × 10−14 |
| Quantity of lymphatic system cells | 1.97 × 10−13 |
| Quantity of lymphocytes | 5.29 × 10−13 |
| Cell movement of leukocytes | 6.80 × 10−13 |
| Proliferation of blood cells | 1.21 × 10−12 |
| Proliferation of immune cells | 1.62 × 10−12 |
| B |
| Diseases or Functions Annotation | p-Value |
| Cutaneous melanoma | 1.52 × 10−12 |
| Skin tumor | 5.94 × 10−12 |
| Melanoma | 1.01 × 10−11 |
| Skin cancer | 1.20 × 10−11 |
| Malignant neuroendocrine neoplasm | 2.45 × 10−7 |
| Small cell lung carcinoma | 3.07 × 10−7 |
| Olfactory response | 3.73 × 10−7 |
| Neuroendocrine tumor | 4.48 × 10−7 |
| Extrapancreatic neuroendocrine tumor | 5.84 × 10−7 |
| Blue round small cell tumor | 7.16 × 10−6 |
Table 3.
Diseases or Functions Annotations in common between methylation-profiling microarray data and targeted methylation sequencing data (data from IPA Core Analysis).
| A |
| Diseases or Functions Annotation | p-Value (Microarray) | p-Value (Methyl-Seq) |
| Leukocyte migration | 2.93 × 10−26 | 4.53 × 10−7 |
| Quantity of lymphatic system cells | 3.30 × 10−25 | 4.34 × 10−6 |
| Quantity of leukocytes | 1.51 × 10−25 | 3.42 × 10−6 |
| Quantity of lymphocytes | 1.53 × 10−24 | 4.75 × 10−6 |
| Cell movement of leukocytes | 5.69 × 10−23 | 1.38 × 10−10 |
| Activation of cells | 2.86 × 10−22 | 5.05 × 10−14 |
| Migration of cells | 1.08 × 10−21 | 7.35 × 10−7 |
| Proliferation of lymphatic system cells | 1.68 × 10−21 | 1.62 × 10−6 |
| Proliferation of lymphocytes | 5.96 × 10−21 | 2.09 × 10−6 |
| Proliferation of immune cells | 3.46 × 10−20 | 1.58 × 10−6 |
| B |
| Diseases or Functions Annotation | p-Value (Microarray) | p-Value (Methyl-Seq) |
| Cross-linkage of protein | 1.60 × 10−4 | 8.28 × 10−4 |
| Skin carcinoma | 7.37 × 10−4 | 3.95 × 10−3 |
| Skin squamous cell carcinoma | 9.61 × 10−4 | 2.69 × 10−4 |
| Relaxation of heart ventricle | 1.03 × 10−3 | 5.24 × 10−3 |
| Surface area of ventricular myocytes | 1.22 × 10−3 | 6.15 × 10−3 |
| Gastro-esophageal carcinoma | 3.77 × 10−3 | 2.78 × 10−3 |
| Chemosensitivity of glioblastoma cells | 4.03 × 10−3 | 9.20 × 10−3 |
| Pancreatic lesion | 5.88 × 10−3 | 6.34 × 10−3 |
| Formation of solid tumor | 5.90 × 10−3 | 1.74 × 10−3 |
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