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Review

Application of Graphene in Tissue Engineering of the Nervous System

by
Karolina Ławkowska
1,*,
Marta Pokrywczyńska
1,
Krzysztof Koper
2,
Luis Alex Kluth
3,
Tomasz Drewa
1 and
Jan Adamowicz
1 on behalf of the Trauma and Reconstructive Urology Working Party of the European Association of Urology Young Academic Urologists
1
Department of Regenerative Medicine, Collegium Medicum, Nicolaus Copernicus University, Curie-Skłodowskiej 9, 85-094 Bydgoszcz, Poland
2
Department of Clinical Oncology and Nursing, Collegium Medicum, Nicolaus Copernicus University, Curie-Skłodowskiej 9, 85-094 Bydgoszcz, Poland
3
Department of Urology, University Medical Center Frankfurt a.M., 60590 Frankfurt am Main, Germany
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2022, 23(1), 33; https://doi.org/10.3390/ijms23010033
Submission received: 2 November 2021 / Revised: 7 December 2021 / Accepted: 16 December 2021 / Published: 21 December 2021
(This article belongs to the Special Issue Novel Biomaterials for Regenerative Medicine)

Abstract

Graphene is the thinnest two-dimensional (2D), only one carbon atom thick, but one of the strongest biomaterials. Due to its unique structure, it has many unique properties used in tissue engineering of the nervous system, such as high strength, flexibility, adequate softness, electrical conductivity, antibacterial effect, and the ability to penetrate the blood–brain barrier (BBB). Graphene is also characterized by the possibility of modifications that allow for even wider application and adaptation to cell cultures of specific cells and tissues, both in vitro and in vivo. Moreover, by using the patient’s own cells for cell culture, it will be possible to produce tissues and organs that can be re-transplanted without transplant rejection, the negative effects of taking immunosuppressive drugs, and waiting for an appropriate organ donor.
Keywords: graphene; graphene-based nanomaterials; tissue engineering; nervous system; cell culture graphene; graphene-based nanomaterials; tissue engineering; nervous system; cell culture

Share and Cite

MDPI and ACS Style

Ławkowska, K.; Pokrywczyńska, M.; Koper, K.; Kluth, L.A.; Drewa, T.; Adamowicz, J., on behalf of the Trauma and Reconstructive Urology Working Party of the European Association of Urology Young Academic Urologists. Application of Graphene in Tissue Engineering of the Nervous System. Int. J. Mol. Sci. 2022, 23, 33. https://doi.org/10.3390/ijms23010033

AMA Style

Ławkowska K, Pokrywczyńska M, Koper K, Kluth LA, Drewa T, Adamowicz J on behalf of the Trauma and Reconstructive Urology Working Party of the European Association of Urology Young Academic Urologists. Application of Graphene in Tissue Engineering of the Nervous System. International Journal of Molecular Sciences. 2022; 23(1):33. https://doi.org/10.3390/ijms23010033

Chicago/Turabian Style

Ławkowska, Karolina, Marta Pokrywczyńska, Krzysztof Koper, Luis Alex Kluth, Tomasz Drewa, and Jan Adamowicz on behalf of the Trauma and Reconstructive Urology Working Party of the European Association of Urology Young Academic Urologists. 2022. "Application of Graphene in Tissue Engineering of the Nervous System" International Journal of Molecular Sciences 23, no. 1: 33. https://doi.org/10.3390/ijms23010033

APA Style

Ławkowska, K., Pokrywczyńska, M., Koper, K., Kluth, L. A., Drewa, T., & Adamowicz, J., on behalf of the Trauma and Reconstructive Urology Working Party of the European Association of Urology Young Academic Urologists. (2022). Application of Graphene in Tissue Engineering of the Nervous System. International Journal of Molecular Sciences, 23(1), 33. https://doi.org/10.3390/ijms23010033

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