The Role of Extracellular Vesicles in the Progression of Human Neuroblastoma
Abstract
:1. Extracellular Vesicles: An Overview
2. Characterization of Neuroblastoma-Derived EV
2.1. Neuroblastoma
2.2. Liquid Biopsies
2.3. Presence of miRNAs
2.4. Proteomic Analysis
3. Release of EV: A Form of Bi-Directional Cross-Talk Between NB Cells and Other Cell Populations
3.1. Delivery of NB-Derived EV to Mesenchymal Stem Cells
3.2. Delivery of EV to Other NB Cells
3.3. EV Released by Immune Cells May Modulate NB Cell Growth
4. Immunosuppressive Functions of NB-Derived EV
5. EV Released by NB May Predict Response to Chemotherapy
6. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Marimpietri, D.; Airoldi, I.; Faini, A.C.; Malavasi, F.; Morandi, F. The Role of Extracellular Vesicles in the Progression of Human Neuroblastoma. Int. J. Mol. Sci. 2021, 22, 3964. https://doi.org/10.3390/ijms22083964
Marimpietri D, Airoldi I, Faini AC, Malavasi F, Morandi F. The Role of Extracellular Vesicles in the Progression of Human Neuroblastoma. International Journal of Molecular Sciences. 2021; 22(8):3964. https://doi.org/10.3390/ijms22083964
Chicago/Turabian StyleMarimpietri, Danilo, Irma Airoldi, Angelo Corso Faini, Fabio Malavasi, and Fabio Morandi. 2021. "The Role of Extracellular Vesicles in the Progression of Human Neuroblastoma" International Journal of Molecular Sciences 22, no. 8: 3964. https://doi.org/10.3390/ijms22083964